中国学术期刊综合评价数据库统计源期刊
中国学术期刊影响因子统计源期刊
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  • Magnetocardiography from ultra-weak magnetic measurement to clinical application research: technological system, evidence progress, and collaborative development roadmap
    FANG Jiancheng, ZHANG Yadan, CUI Peiling, CUI Yangyang, XU Dong
    Practical Electrocardiology and Clinical Treatment. 2026, 35(1): 5-8. https://doi.org/10.13308/j.issn.2097-5716.xd20260025
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    Magnetocardiography ( MCG), a technique that measures the weak magnetic field generated by human electrophysiological activities, provides non-invasive, ionizing-radiation-free functional information.Compared with traditional structural imaging techniques, MCG can capture functional changes in the early stages of diseases, making it particularly suitable for early screening and disease progression assessment. In recent years,rapid advancements in quantum magnetic sensors, magnetic shielding, and active compensation technologies have enabled MCG to overcome the limitations of low-temperature superconductivity and magnetically shielded rooms gradually, developing in the direction of greater convenience and lower cost. However, despite its significant potential in clinical applications such as chest pain triage, coronary heart disease screening, and myocardial ischemia assessment, the clinical translation of MCG still faces challenges including insufficient specificity and lack of standardization. Furthermore, variations in equipment and signal processing methods lead to low comparability among research findings. This article reviews the development history and current application status of MCG technology, synthesizes the research progress of our team over the past three years, discusses the bottlenecks in applying MCG across different clinical settings, and proposes that future research should focus on areas such as physical mechanisms, feature interpretability, establishing quantitative relationships between diseases, and improving clinical diagnostic specificity. These efforts aim to promote the standardization of MCG, and advance its research and application in the fields of cardiology, neurology, oncology, and traditional Chinese medicine.

  • Research progress in clinical characteristics and significance of complete right bundle branch block
    MOU Huan, ZHANG Quan
    Practical Electrocardiology and Clinical Treatment. 2025, 34(5): 777-780. https://doi.org/10.13308/j.issn.2097-5716.2025.05.031
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    Complete right bundle branch block (CRBBB) is a common electrocardiographic abnormality observed across all age groups. It is characterized by delayed conduction or anatomical rupture in the right bundle branch, resulting in delayed depolarization of the right ventricle after the left ventricle. This conduction disorder often coexists with various cardiovascular diseases, such as atrial fibrillation, coronary heart disease, heart failure, and cardiomyopathies, with its incidence varying significantly among different populations. Historically, CRBBB was usually considered to have limited clinical significance. However, recent studies indicate that it has important clinical significance not only in patients with structural heart diseases but also in newonset cases, general population, and athletes.
  • Artificial intelligence-enabled electrocardiogram interpretation in cardiovascular disease: a systematic review of current landscape
    MAHEMUTI Zilalan, FAN Ping
    Practical Electrocardiology and Clinical Treatment. 2025, 34(5): 631-636. https://doi.org/10.13308/j.issn.2097-5716.2025.05.002
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    Electrocardiogram (ECG) serves as a crucial tool for diagnosing cardiovascular diseases. With the rapid advancement of artificial intelligence (AI) technology, the application of AI in ECG analysis has gradually become a research hotspot. AI technology not only enables automated and accurate ECG interpretation, but also significantly improves the efficiency and accuracy of largescale cardiovascular disease screening in populations. This review summarizes the latest progress in AIassisted ECG analysis for cardiovascular system diseases, with a focus on its applications in arrhythmias, structural heart diseases, and acute cardiovascular events. Furthermore, it discusses development directions. As explainable AI technology evolves in the future, AIECG models are expected to be more widely adopted in clinical practice.
  • Therapeutic effect of low-flow oxygen inhalation on elderly patients with hypertension complicated by obstructive sleep apnea syndrome
    SUN Xia, CUI Xinggang, ZHONG Wei, CHEN Guanghua, DAI Zhiyin, YUAN Wei, ZHANG Chaopu
    Practical Electrocardiology and Clinical Treatment. 2025, 34(5): 654-658. https://doi.org/10.13308/j.issn.2097-5716.2025.05.006
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    Objective To analyze the therapeutic effect of low-flow oxygen inhalation in elderly patients with hypertension complicated by obstructive sleep apnea syndrome (OSAS). Methods A total of 175 elderly patients with hypertension and OSAS were selected as study subjects. All patients received conventional antihypertensive medication as recommended by guidelines. Those receiving continuous positive airway pressure (CPAP) therapy, low-flow oxygen inhalation therapy, and no corresponding intervention were assigned to a CPAP group (55 cases), a low-flow oxygen group (60 cases), and a control group (60 cases), respectively. Clinical data were collected, including body mass index, waist circumference, underlying diseases, laboratory test results and color Doppler echocardiography parameters, as well as systolic/diastolic blood pressure, Epworth sleepiness scale (ESS) scores, nocturnal minimum saturation of peripheral oxygen (SpO2), and apnea hypopnea index (AHI) before and after intervention (3 months of treatment). ResultsBlood pressure control and respiratory parameters in the low-flow oxygen group both improved significantly after oxygen inhalation (both P<0.05). After 3 months of follow-up, the nocturnal minimum SpO2 in both the low-flow oxygen and CPAP groups increased significantly compared with pre-intervention levels (both P<0.01). There was statistically significant difference in nocturnal minimum SpO2 after intervention among the three groups (P<0.01). After pharmacotherapy or intervention, systolic and diastolic blood pressures both decreased significantly in all the three groups compared with pre-intervention levels (all P<0.05), and post-intervention differences in systolic and diastolic blood pressures among the three groups were statistically significant (all P<0.05). Compared with baseline, both the low-flow oxygen group and the CPAP group demonstrated significant reduction in ESS score and AHI after the intervention (both P<0.05). Conclusion Low-flow oxygen inhalation therapy in elderly patients with hypertension and OSAS could partially improve sleep respiratory parameters, increase nocturnal SpO2, and help to increase the compliance rate of blood pressure control, reduce the use of antihypertensive medication and alleviate economic burden.
  • Application of ABC-X model-based nursing intervention in patients with mild cognitive impairment
    WANG Caixing, JIANG Guiyan, LIANG Jinqing
    Practical Electrocardiology and Clinical Treatment. 2026, 35(1): 117-122. https://doi.org/10.13308/j.issn.2097-5716.xd20250332
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    Objective  To explore the value of ABC-X model-based nursing intervention applied in patients with mild cognitive impairment (MCI). Methods  A total of 100 MCI patients were selected, and randomly divided into an observation group and a control group using a random number table method, with 50 cases in each group. The observation group received the ABC-X model-based nursing intervention, while the control group received conventional nursing care. The self-rating anxiety scale (SAS), self-rating depression scale (SDS), Montreal cognitive assessment (MoCA) scale, and 36-item short form health survey (SF-36) scores were compared between the two groups before the intervention and after 4 weeks of intervention. Results  Before the nursing intervention, there were no statistically significant differences in SAS score, SDS score, total MoCA scale score, or the average SF-36 score between the two groups (all P>0.05). After 4 weeks of intervention, the SAS and SDS scores in the observation group were both significantly lower than those in the control group (all P<0.01), while the total MoCA scale score and the average SF-36 score were both significantly higher in the observation group than those in the control group (both P<0.01). Conclusion  The application of the ABC-X model-based nursing intervention in MCI patients could effectively alleviate negative emotions, improve cognitive function, and further enhance their quality of life, thereby making it highly recommended for widespread use.

  • Impact of myocardial infarction on clinical features and outcomes in septic patients: a real-world analysis based on MIMIC-Ⅳ database
    BAI Shasha, DU Yingqiang, LI Mohan, LI Biao
    Practical Electrocardiology and Clinical Treatment. 2025, 34(6): 792-798. https://doi.org/10.13308/j.issn.2097-5716.2025.06.003
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    Objective  To systematically analyze the clinical characteristics of septic patients complicated by myocardial infarction (MI), evaluate its impact on in-hospital mortality, and to explore related influencing factors and prognostic indicators. Methods  Based on the MIMIC-Ⅳ v2.0 database, a total of 12 838 adult septic patients meeting the Sepsis-3 diagnostic criteria were included. They were divided into two groups according to the presence of MI: a sepsis with MI group (n=2 236) and a sepsis-alone group (n=10 602). Demographic data, clinical indicators, and outcomes were compared between the two groups. Multivariate Logistic regression and random forest models were used to identify key predictors of in-hospital mortality, and subgroup stratification analysis was performed. Results  Septic patients with MI were older, had a higher proportion of males, a significantly higher prevalence of diabetes and chronic obstructive pulmonary disease (COPD), and higher APACHE-Ⅲ and SAPS-Ⅱ scores than those in the sepsis-alone group (all P<0.05). The in-hospital mortality rate in the sepsis with MI group was 25.2%, significantly higher than that in the sepsis-alone group (19.9%, P<0.001). Multivariate Logistic regression analysis showed that MI was an independent risk factor of in-hospital mortality (OR=1.26, 95% CI 1.11-1.43). Subgroup analysis revealed that in patients with MI, COPD, hypoalbuminemia, and low platelet count were significantly associated with an increased risk of death, while diabetes showed a protective effect in patients without MI. The random forest model further validated the importance of these variables in predicting mortality risk. Additionally, statin use was associated with reduced 90-day mortality in septic patients with MI. Conclusion  MI significantly aggravates the condition of septic patients and increases the risk of in-hospital mortality, highlighting the importance of early risk stratification and intervention. Predictive models combining multivariate statistics and machine learning may facilitate more accurate individualized prognostic assessment.

  • Heart rate variability characteristics in patients with depression and their clinical significance
    ALIMU Alimire, ZHANG Yi, FENG Yan, ALIMU Alide
    Practical Electrocardiology and Clinical Treatment. 2025, 34(6): 910-916. https://doi.org/10.13308/j.issn.2097-5716.2025.06.027
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    Depression is a mental disorder characterized by high prevalence and substantial disease burden. Its pathophysiological process is closely associated with dysfunction of the autonomic nervous system. Heart rate variability (HRV), a non-invasive and quantitative indicator for assessing autonomic nervous function, provides a crucial window into revealing the pathophysiological mechanisms of depression. This article systematically reviews the HRV characteristics in patients with depression, related pathophysiological mechanisms, challenges in practical measurement, and its applications in diagnosis and treatment, aiming to explore the potential value and application prospects of HRV as a biomarker for precision management in depression.

  • Predictive value of transesophageal echocardiography for left atrial appendage thrombus in patients with atrial fibrillation
    HUANG Xiaoyan, MEN Xiaoyu, ZHANG Cuiping, CHEN Keke, LI Yan
    Practical Electrocardiology and Clinical Treatment. 2026, 35(1): 24-29. https://doi.org/10.13308/j.issn.2097-5716.xd20250404
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    Objective To investigate the application value of transesophageal echocardiography ( TEE) in diagnosing left atrial appendage thrombus (LAAT) among patients with atrial fibrillation (AF), and to analyze the impact of echocardiographic parameters and clinical factors on the diagnosis of LAAT by TEE. Methods Clinical data of 326 AF patients who had undergone TEE examination were retrospectively analyzed. Patients were divided into LAAT positive group ( n = 52) and negative group ( n = 274) according to TEE results. Patients' general information, AF type and duration, echocardiographic parameters, and TEE findings were recorded. Univariate analysis was performed. ROC curves were used to evaluate the predictive efficacy of left atrial appendage peak flow velocity (LAAV) and left atrial appendage area (LAAA) for LAAT. Independent influencing factors for LAAT in AF patients were identified via Logistic regression analysis. The Hosmer-Lemeshow test and decision curve analysis were employed to assess the goodness-of-fit and clinical utility of the predictive model. Results TEE detected LAAT in 52 (16. 0%) AF patients. Compared with the LAAT negative group, patients in the LAAT positive group were older, had longer AF duration, higher CHA2DS2-VASc scores, larger left atrial diameter (LAD) and LAAA,lower LAAV, and a higher proportion of persistent or permanent AF (all P<0. 05). For predicting thrombus, the area under the curve (AUC) was 0. 893 for LAAV, with an optimal cutoff value of 25. 6 cm / s, sensitivity of 82. 7%, and specificity of 84. 3%. The AUC value for LAAA was 0. 812, with an optimal cutoff value of 5. 2 cm2,sensitivity of 76. 9%, and specificity of 75. 5%. The combined prediction of LAAV and LAAA increased the AUC value to 0. 921, which was significantly higher than the predictive efficacy of LAAV or LAAA used alone (both P<0. 05). Logistic regression analysis identified longer AF duration (OR = 1. 089), decreased LAAV (OR = 0. 876),and larger LAAA (OR = 1. 626) as independent risk factors for LAAT (all P<0. 05). The Hosmer-Lemeshow test indicated good model fit ( P = 0. 587 ), and decision curve analysis confirmed its good clinical utility.Conclusion TEE is an effective tool for diagnosing LAAT in AF patients. Longer AF duration, decreased LAAV,and larger LAAA are independent risk factors for LAAT formation. The combined application of LAAV and LAAA could significantly enhance the predictive value for LAAT, and may serve as an important screening indicator inTEE examinations.

  • Application value of non-invasive prenatal testing in screening for fetal chromosomal copy number variations
    JU Aiping, MENG Xiangrong, QIN Yanling, GU Yuying
    Practical Electrocardiology and Clinical Treatment. 2025, 34(5): 665-671. https://doi.org/10.13308/j.issn.2097-5716.2025.05.008
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    Objective To explore the clinical performance of non-invasive prenatal testing (NIPT) in screening for fetal chromosomal copy number variations (CNVs). Methods In this retrospective cohort study, 196 high-risk NIPT samples were analyzed. The results of chromosomal karyotyping analysis or chromosomal microarray analysis (CMA) were compared. The positive rate and positive predictive value (PPV) of fetal CNVs, and other clinical data were screened by NIPT, so as to assess the detection value of NIPT for fetal CNVs. Results A total of 20 378 NIPT samples were tested. Among the 196 high-risk samples, 54 were CNVs, with a screening positive rate of 0.265%. Forty-six pregnant women underwent interventional prenatal diagnosis, among whom there were 21 cases confirmed with CNVs including 13 cases with pathogenic variations, 3 cases with likely pathogenic variations, and 5 cases with variations of unknown significance. The PPV of NIPT for screening CNVs was 45.65%. Seventeen cases of microdeletion CNVs and 36 cases of microduplication CNVs were screened out by NIPT, and 1 case was microdeletion combined with microduplication CNVs, accounting for 31.48% (17/54), 66.67% (36/54), and 1.85% (1/54), respectively. The corresponding PPVs were 64.29%, 35.48% and 100.00%, respectively. Statistical analysis showed that there were no statistically significant differences in the positive rate and PPV of NIPT for screening microdeletion CNVs and microduplication CNVs (all P>0.05). Conclusion NIPT demonstrates relatively high positive rate and PPV for screening fetal CNVs. Interventional prenatal diagnosis should be recommended for those with high-risk of CNVs by NIPT. NIPT combined with chromosomal karyotyping analysis and CMA could provide precise genetic counseling and guidance for clinical practice.
  • Analysis of short-term efficacy of laparoscopic proximal gastrectomy with tubular gastroesophageal circular anastomosis for early-stage esophagogastric junction adenocarcinoma
    YIN Kai, HAN He, SHI Xianhong, FAN Xin, DANG Shengchun, QU Jianguo, CHEN Jixiang
    Practical Electrocardiology and Clinical Treatment. 2025, 34(6): 811-816. https://doi.org/10.13308/j.issn.2097-5716.2025.06.006
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    Objective  To evaluate the short-term efficacy of proximal gastrectomy combined with tubular gastroesophageal circular anastomosis in the treatment of earlystage esophagogastric junction adenocarcinoma (EGJA). Methods  Clinical data of 7 patients with early-stage EGJA who had undergone this procedure were retrospectively analyzed. Parameters included baseline characteristics, perioperative indicators, and follow-up outcomes, with a focus on perioperative status, complication incidence, postoperative nutritional status and gastroesophageal reflux. Results  All the 7 patients successfully underwent laparoscopy-assisted proximal gastrectomy with tubular gastroesophageal circular anastomosis. The mean operative time was (227.1±51.9) minutes, the mean anastomosis time was (54.4±10.0) minutes, and the mean intraoperative blood loss was (47.1±28.7) mL. The mean time to first flatus was (3.3±1.3) days, while the mean hospital stay was (21.1±7.6) days. After the procedure, one patient developed an anastomotic leak, with no other complications recorded. At the 6-month follow-up, the mean serum albumin level was (39.2±3.4) g/L, the mean hemoglobin level was (124.6±13.8) g/L, and the mean gastroesophageal reflux disease questionnaire score was (3.1±0.9) points. Both gastroscopy and upper gastrointestinal radiography with iodinated contrast studies showed no significant signs of reflux esophagitis. Conclusion  Laparoscopic proximal gastrectomy with tubular gastroesophageal circular anastomosis is a safe and feasible approach for patients with early-stage EGJA. Initial findings suggest that this technique demonstrates reliable anti-reflux efficacy, helps to reduce the risk of postoperative reflux esophagitis, and contributes to improved quality of life after surgery.
  • Application of case-based teaching method combined with problem-based learning model in stroke green channel teaching
    JIANG Wan, XU Yun, YE Qing
    Practical Electrocardiology and Clinical Treatment. 2026, 35(1): 135-139. https://doi.org/10.13308/j.issn.2097-5716.xd20240448
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    Objective  To evaluate the effectiveness of case-based teaching method combined with problem-based learning model applied in stroke green channel teaching. Methods  A total of 50 residents undergoing standardized training in the Department of Neurology were selected, and randomly divided into two groups, each consisting of 25 residents. The control group received traditional lecture-based teaching, while the study group was taught using case-based teaching method combined with problem-based learning model. The learning outcomes and teaching satisfaction were assessed through multiple dimensions including theoretical exams, case analysis, and self-learning ability. Results  The study group demonstrated significantly better performances in clinical thinking ability, self-learning ability, team collaboration ability, and teaching satisfaction compared to the control group (P<0.05), while no significant difference was found in the mastery of theoretical knowledge between the two groups. Conclusion  Case-based teaching method combined with problem-based learning model has a significant advantage in enhancing the effectiveness of stroke green channel teaching, markedly improving students clinical thinking abilities, self-learning capabilities, and team collaboration abilities, and is widely welcomed by students. It is recommended for being promoted and applied in medical education.

  • Research trends of artificial intelligence in field of hypertension: a CiteSpace visual analysis based on literature of 2015-2024
    YUAN Yanling, MA Mingren, SUN Li, AN Yongchao, ZHAO Xuehong, LIU Yan
    Practical Electrocardiology and Clinical Treatment. 2026, 35(1): 78-87. https://doi.org/10.13308/j.issn.2097-5716.xd20250333
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    Objective  To review the research status and hotspots in the artificial intelligence (AI) application of the hypertension field over the past decade using bibliometric methods, and to provide references for future related research in the future. Methods  The Web of Science Core Collection database was used as the data source to retrieve literature published between January 1, 2015 and December 31, 2024, on the application of AI in the field of hypertension. CiteSpace 6.3.R1 software was employed to conduct visual mapping analysis of annual publication volume, countries/regions, research institutions, authors, co-citation networks, and key words. Results  A total of 654 articles were included. Between 2015 and 2024, although there were fluctuations in parts of these years, the annual publication volume in the field of AI applied to hypertension showed a general upward trend, with particularly notable growth after 2020. China had the highest volume of publications, while the United States showed the highest centrality index. The Chinese Academy of Sciences was the institution with the highest publication volume. Acharya UR, Mulatero P, and Li Y were the authors with the highest publication outputs. The top three authors ranked by co-citation frequency, Kachuee M, O Brien E, and Whelton PK, made significant contribution to this field. The most frequently co-cited literature was “Cuffless blood pressure estimation algorithms for continuous health-care monitoring”. Hypertension, J Hypertens, and Circulation were the top three journals in terms of influence. Research hotspots primarily focused on the prediction and early identification of hypertension, non-invasive continuous blood pressure monitoring, diagnosis, risk assessment, and intelligent clinical decision support. Conclusion  The application of AI in the field of hypertension shows broad prospects. Future research could focus on multimodal data fusion, optimization of non-invasive continuous blood pressure monitoring technology, improvement of AI-assisted clinical decision support systems, integrated application of digital health technologies, and in-depth studies on specific hypertensive populations.

  • Application of wearable 12-lead ambulatory electrocardiography recorders in remote diagnosis and treatment of cardiovascular diseases
    AIHAIMAITI Pazilaiti, JIANG Xing, AINIWA Mubalake, LIU Wanping, FAN Ping
    Practical Electrocardiology and Clinical Treatment. 2025, 34(5): 637-640. https://doi.org/10.13308/j.issn.2097-5716.2025.05.003
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    Objective To explore the application value of wearable electrocardiographic (ECG) monitoring devices in the remote diagnosis and treatment of cardiovascular and cerebrovascular diseases. Methods A total of 16 117 ECG reports collected via wearable ECG devices from community health centers in Kuche City of Xinjiang Uygur Autonomous Region were randomly selected. The analysis focused on the detection rate of abnormal ECGs, the identification of critical values and warning-level ECG findings, as well as the clinical outcomes of cases with critical values. Results The study included 16 117 valid ECG recordings. The average age of the participants was 54.5 years, with 7 256 (45.02%) males and 8 861 (54.98%) females. Among these ECGs, 4 985 cases were abnormal, including 45 (0.28%) with critical values and 548 cases (3.40%) of warning ECGs. Of the 45 cases with critical values, 2 (4.44%) were lost to follow-up, 15 (33.33%) refused medical advice, 5 (11.11%) died despite rescue efforts at local hospitals, and 22 (48.89%) followed the recommendation to seek medical care. Among these 22 cases, the time from receiving the ECG diagnosis to presenting at the hospital ranged from 41 to 436 minutes, with an average duration of 108.95 minutes. After seeking medical attention, 6 cases were discharged after observation and improvement, 9 received pharmacological treatment, and 7 underwent surgical procedures. Among the 7 surgical cases, the time from admission to surgery ranged from 16 to 372 minutes, averaging 101.86 minutes. Of these cases, 5 (71.43%) underwent coronary stent implantation, 1 (14.29%) was transferred to a higher-level hospital for coronary artery bypass grafting, and 1 (14.29%) received pacemaker implantation. One case died despite rescue efforts. Conclusion Wearable ECG monitoring devices enable remote ECG monitoring and early risk warning, facilitating timely medical intervention, reducing the risk of cardiovascular events, and demonstrating significant application value.
  • Predictive value of systemic immune-inflammation index for ventricular arrhythmia after PCI in patients with acute myocardial infarction
    ZHENG Feng, XU Liangjie, WANG Jianfei, XU Li, CHEN Xing
    Practical Electrocardiology and Clinical Treatment. 2025, 34(6): 781-786. https://doi.org/10.13308/j.issn.2097-5716.2025.06.001
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    Objective  To investigate the predictive value of systemic immune-inflammation index (SII) for the occurrence of ventricular arrhythmia (VA) after percutaneous coronary intervention (PCI) in patients with acute myocardial infarction (AMI). Methods  A total of 100 AMI patients undergoing emergency PCI were consecutively enrolled, and divided into a VA group (n=52) and a non-VA group (n=48) based on the occurrence of VA within 7 days after PCI. Clinical baseline data and laboratory test results were collected. Complete blood count parameters included white blood cell, neutrophil, lymphocyte, and platelet counts, which were used to calculate SII, neutrophil to lymphocyte ratio (NLR), and platelet to lymphocyte ratio (PLR). Cardiac ultrasound was performed to assess left ventricular end-diastolic diameter (LVEDD), left ventricular end-diastolic volume (LVEDV), and LVEF. Logistic regression analysis was used to identify factors influencing VA occurrence within 7 days after PCI. The predictive performance was evaluated using ROC curve analysis, and the dose-response relationship was assessed with restricted cubic spline (RCS) plots. Results  The VA group had significantly higher levels of SII, PLR, NLR, LVEDD and LVEDV, and significantly lower LVEF compared to the non-VA group (all P<0.05). Multivariate Logistic regression analysis indicated that SII was an independent risk factor for VA within 7 days after PCI in AMI patients (OR=1.01, P<0.01). RCS plot analysis revealed a non-linear positive correlation between SII and the risk of VA (P=0.002). ROC curve analysis showed that the optimal cut-off value of SII for predicting VA was 973×109/L, with a sensitivity of 81% and a specificity of 71%. Conclusion  SII>973×109/L could serve as a potential predictor for VA after PCI in AMI patients, providing valuable insight for early identification of high-risk patients and guiding clinical intervention.
  • Research advances in cancer-related atrial fibrillation
    HAN Dandan, LIU Jijun, ZHU Hong, PEI Yuanyuan, LIU Yinchao, CHEN Xiyuan, WEI Yang, WANG Chao
    Practical Electrocardiology and Clinical Treatment. 2025, 34(6): 904-909. https://doi.org/10.13308/j.issn.2097-5716.2025.06.026
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    Cancer-related atrial fibrillation (CR-AF) is a common complication in cancer patients, closely associated with the tumor itself, anti-cancer treatments, and systemic inflammatory responses. With advances in cancer treatment and prolonged survival of patients, the incidence of CR-AF has increased significantly, making it an important research focus in the field of cardio-oncology. Atrial fibrillation is particularly prevalent among patients with lung, breast, or esophageal cancers. CR-AF significantly elevates the risk of stroke, heart failure, and systemic embolism, thereby adversely affecting patients' quality of life and long-term prognosis. The pathogenesis of CR-AF involves multiple mechanisms, including tumor-induced systemic inflammation, oxidative stress, and atrial structural remodeling, while the cardiotoxic effects of chemotherapy and radiotherapy may also promote the occurrence of atrial fibrillation. Although the clinical significance of CR-AF is gaining increasing attention, currently used assessment tools for atrial fibrillation risk such as CHA2DS2-VASc and HAS-BLED have limitations in cancer populations. Moreover, anticoagulation therapy faces the challenge of balancing thrombotic and bleeding risks. Future research should focus on precise risk assessment, individualized treatment strategies, and early intervention to improve overall treatment outcomes and quality of life in cancer patients.

  • Research on risk factors for calcific aortic valve disease
    QIAN Duoduo, JIANG Kun, LIAN Xiaoqing, CHEN Xiangxuan, TAO Qin, ZHANG Yuqing, FANG Xu
    Practical Electrocardiology and Clinical Treatment. 2025, 34(6): 824-829. https://doi.org/10.13308/j.issn.2097-5716.2025.06.008
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    Objective  To investigate the risk factors associated with calcific aortic valve disease (CAVD), and to provide a basis for clinical guidance and intervention. Methods  A retrospective analysis was conducted on 184 patients diagnosed with CAVD by echocardiography. Clinical data and information on comorbidities were collected, and 217 subjects with normal aortic valve morphology were selected as a control group. Multivariate Logistic regression analysis was used to identify independent risk factors and related predisposing factors for CAVD. Results  Advanced age, coronary heart disease, heart failure, renal insufficiency, or cerebral infarction were associated with a higher risk of CAVD. Among these, advanced age and renal insufficiency were independent risk factors for CAVD. Analysis of laboratory indicators suggested that lipoprotein(a) may be an independent risk factor for CAVD, and monitoring this indicator could help identify high-risk populations. ConclusionThe occurrence of CAVD is closely related to advanced age and renal insufficiency, and elevated lipoprotein(a) may also be involved in its pathogenesis.

  • Construction and application of an Internet-based remote electrocardiogram monitoring system under regional collaborative medical care model
    ZHANG Rong, ZHANG Luxing, LIN Junfang, ZHANG Gaifang, WANG Fen, ZHANG Yueyuan, DONG Chen
    Practical Electrocardiology and Clinical Treatment. 2025, 34(6): 930-936. https://doi.org/10.13308/j.issn.2097-5716.2025.06.030
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    The Internet-based remote electrocardiogram (ECG) platform centered on Xi'an International Medical Center Hospital has successfully integrated 80 medical institutions, establishing a multi-dimensional remote diagnosis and treatment network that encompasses routine ECG and ambulatory electrocardiography monitoring, and wearable device and dynamic blood pressure monitoring. The project has served over 100 000 patients cumulatively, with an average monthly data processing volume of 5 000 cases. It has effectively promoted the implementation of hierarchical medical treatment system and early warning mechanisms for cardiovascular diseases. Against the background of the deep integration of information technology and healthcare, Internet-based medical services are experiencing rapid development. This paper systematically analyzes the practical value of this model from multiple dimensions, including technical architecture, data management, clinical efficacy, and health economics, aiming to provide valuable insights for the collaborative development of regional healthcare.

  • Clinical characteristics and identification methods of patients with non-ST-segment elevation myocardial infarction and coronary artery occlusion: a simplified risk score model
    DAI Zhiyin, XU Shuxian, ZHONG Wei
    Practical Electrocardiology and Clinical Treatment. 2026, 35(1): 9-13. https://doi.org/10.13308/j.issn.2097-5716.xd20250447
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    Objective To develop a simplified risk score model based on clinical features for the early identification of coronary artery occlusion (CAO) in patients with non-ST-segment elevation myocardial infarction (NSTEMI). Methods A total of 182 patients with NSTEMI were enrolled, and divided into a CAO group ( n =91) and a non-CAO group (n = 91) based on coronary angiography findings. We collected clinical data including history of myocardial infarction or cerebral infarction, hypotension, heart failure, segmental wall motion abnormalities indicated by echocardiography, acute mitral regurgitation, persistent chest pain, and chest pain refractory to optimal medical therapy. Chi-square tests were used to analyze intergroup differences, and Logistic regression analysis was applied to assess the predictive value of the above features for CAO. Variables with predictive significance were assigned scores approximating their regression coefficients in the Logistic regression model if positive, or 0 if negative. The simplified risk score was derived by summing the scores of all variables. The diagnostic cut-off value of the score was determined using ROC curve analysis, and the predictive performance of the model for NSTEMI with CAO was evaluated. Results Patients in the CAO group were significantly younger than those in the non-CAO group (P<0. 05). There were no statistically significant differences between the two groups in terms of sex, advanced age, diabetes, hypertension, or smoking history (all P>0. 05). Compared with the non-CAO group, the CAO group had significantly higher proportions of patients with hypotension, heart failure,segmental wall motion abnormalities, persistent chest pain, and chest pain refractory to optimal medical therapy (all P < 0. 05). Logistic regression analysis identified hypotension, heart failure, segmental wall motion abnormalities, persistent chest pain, and chest pain refractory to optimal medical therapy as significant predictors of CAO (all P<0. 05). ROC curve analysis showed that the simplified risk score model had an AUC value of 0. 819(95%CI 0. 757 - 0. 881), with an optimal cut-off value of 3. 1 points, yielding a sensitivity of 72. 5% and a specificity of 81. 3%. Conclusion A simplified risk score model based on clinical features—including hypotension, heart failure, segmental wall motion abnormalities, persistent chest pain, and chest pain refractory to optimal medical therapy—could accurately identify those with CAO among NSTEMI patients.
  • Application value and progress of telemetry electrocardiogram
    ZHANG Xuan, LV Na, WANG Lu, XIAO Chunxia, FAN Yongmei
    Practical Electrocardiology and Clinical Treatment. 2026, 35(1): 158-163. https://doi.org/10.13308/j.issn.2097-5716.xd20250345
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    The electrocardiogram (ECG) examination, as a commonly used diagnostic tool for cardiovascular diseases, holds significant importance in clinical application. However, its interpretation relies heavily on the expertise of cardiologists. In recent years, remote ECG technology has flourished under the dual impetus of policy and technology, demonstrating immense potential in aspects such as promoting the reallocation of high-quality medical resources to grassroots areas, executing the graded diagnosis and treatment system, and enhancing both pre-hospital emergency response and out-of-hospital monitoring frameworks. Particularly, breakthroughs in artificial intelligence and the widespread adoption of wearable devices have significantly energized the application of telemetry ECG. This paper provides a systematic overview of the present state and future prospects of telemetry ECG, focusing on its clinical value and technological advancements.

  • Predictors for arrhythmia associated with acute inferior wall myocardial infarction
    RAO Shuangshuang
    Practical Electrocardiology and Clinical Treatment. 2026, 35(1): 45-50. https://doi.org/10.13308/j.issn.2097-5716.xd20250373
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    Objective  To investigate the predictors of severe arrhythmia in patients with acute inferior wall myocardial infarction (IWMI) during hospitalization. Methods  A total of 82 patients with acute IWMI were enrolled, and divided into an arrhythmia group (n=28) and a non-arrhythmia group (n=54) based on the occurrence of severe arrhythmia during hospitalization. Baseline characteristics, laboratory results, electrocardiogram (ECG), and coronary angiography indexes were collected from both groups. These data included sex, age, diabetes, hypertension, smoking history, Killip classification, time from symptom onset to hospital admission, systolic blood pressure and heart rate on admission, as well as serum potassium, fasting blood glucose (FBG), low-density lipoprotein cholesterol (LDL-C), neutrophil-to-lymphocyte ratio (NLR), troponin I, left ventricular ejection fraction (LVEF), Gensini score, presence of pathological Q waves, ST-segment elevation amplitude, QTc dispersion, right dominant coronary artery supply, and pre-procedural TIMI flow grade. The relationship between the above parameters and the occurrence of arrhythmia was analyzed. Results  Univariate analysis revealed no statistically significant differences between the two groups in terms of sex, age, comorbidities (diabetes and hypertension), smoking history, time from symptom onset to hospital admission, heart rate on admission, LDL-C level, Gensini score, pathological Q waves, ST-segment elevation amplitude, or pre-procedural TIMI flow grade (all P>0.05). However, statistically significant differences were observed in Killip classification, systolic blood pressure on admission, serum potassium, FBG, NLR, troponin I, LVEF, QTc dispersion, and right dominant coronary artery supply (all P<0.05). Multivariate Logistic regression analysis identified Killip class (Ⅲ-Ⅳ), NLR≥5.0, QTc dispersion≥80 ms, and right dominant coronary artery supply as independent risk factors for severe arrhythmia (all P<0.05), while serum potassium ≥3.8 mmol/L was an independent protective factor (P<0.05). Conclusion  High Killip classification, elevated NLR, increased QTc dispersion, right dominant coronary artery supply, and low serum potassium level (<3.8 mmol/L) are strong independent predictors of severe arrhythmia in patients with acute IWMI. These factors facilitate early identification of high-risk patients and guide clinical intervention.

  • Predictive value of left atrial sphericity and mitral regurgitation for recurrence after radiofrequency catheter ablation of atrial fibrillation
    HUANG Chunyan, ZHANG Lei, LI Yaping, DONG Shuguang, ZHANG Yuanheng, LI Dongsheng
    Practical Electrocardiology and Clinical Treatment. 2025, 34(6): 839-842. https://doi.org/10.13308/j.issn.2097-5716.2025.06.011
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    Objective  To investigate the impact of left atrial sphericity (LASP) and functional mitral regurgitation on the maintenance of sinus rhythm after radiofrequency catheter ablation (RFCA) in patients with atrial fibrillation (AF), and to evaluate their correlation with procedural outcomes. Methods  A total of 105 patients undergoing initial RFCA treatment for AF were enrolled, and categorized into a non-recurrence group (66 cases) and a recurrence group (39 cases) based on post-operative follow-up results. General clinical data, and echocardiographic and left atrial CT angiography related parameters ［including left atrial anteroposterior diameter, LVEF, mitral regurgitation area (MRA), left atrial volume, LASP, etc.］ were collected, and made intergroup comparisons. Univariate and multivariate Cox regression analyses were used to identify factors associated with AF recurrence. Results  The left atrial anteroposterior diameter, mitral regurgitation rate, MRA, left atrial volume, and LASP were all significantly higher in the recurrence group compared to the non-recurrence group (all P＜0.05). Cox regression analysis indicated that LASP, mitral regurgitation, and MRA were significantly associated with post-operative recurrence (all P＜0.05). Conclusion  LASP and mitral regurgitation are closely associated with AF recurrence after RFCA, and could serve as reference indicators for predicting post-operative recurrence.

  • Advances in clinical research of pacing-induced cardiomyopathy
    ZHANG Lei, XU Sudan, LI Hongli
    Practical Electrocardiology and Clinical Treatment. 2026, 35(1): 144-151. https://doi.org/10.13308/j.issn.2097-5716.xd20250386
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    Pacemaker-induced cardiomyopathy (PICM) is a serious complication characterized by progressive deterioration of left ventricular systolic function due to chronic right ventricular pacing. With the annual increase in permanent pacemaker implantations, the early identification and effective management of PICM have become key concerns in the field of cardiology. This article systematically reviews the definition, epidemiological features, pathophysiological mechanisms, risk factors, and related predictive models of PICM. Based on current evidences, it evaluates the effect and limitations of preventive and therapeutic strategies including cardiac resynchronization therapy, conduction system pacing, and biological pacing, aiming to provide insights for clinical practice.

  • Research progress of fragmented QRS complex in cardiovascular diseases
    LIU Xuelei, GUO Fangming
    Practical Electrocardiology and Clinical Treatment. 2025, 34(6): 917-920. https://doi.org/10.13308/j.issn.2097-5716.2025.06.028
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    The fragmented QRS complex (fQRS) is an important abnormal manifestation in the electrocardiogram (ECG), and has attracted widespread attention in the field of cardiovascular diseases in recent years. With in-depth research on fQRS, it has been found to be closely associated with coronary heart disease, arrhythmia, hypertension, heart failure, cardiomyopathy and other diseases. It can serve as an important indicator for predicting cardiovascular events and assessing patients' prognosis. This article summarizes the research progress of fQRS in the related fields of cardiovascular diseases, explores its manifestations in the ECG and its clinical significance, so as to provide a reference for the application of fQRS in cardiovascular diseases.

  • Value of ST-segment duration and ST/QT in differential diagnosis of hypertrophic cardiomyopathy and hypertensive ventricular hypertrophy
    ZHANG Wenli, ZHOU Na, ZHANG Yifan
    Practical Electrocardiology and Clinical Treatment. 2025, 34(6): 787-791. https://doi.org/10.13308/j.issn.2097-5716.2025.06.002
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    Objective  To evaluate the clinical utility of ST-segment duration and ST/QT ratio in differentiating between hypertrophic cardiomyopathy (HCM) and hypertensive ventricular hypertrophy (HVH). Methods  A total of 98 subjects were enrolled, including 45 patients without cardiac disease (control group), 22 patients with HCM (HCM group), and 31 patients with HVH (HVH group). All participants underwent electrocardiogram (ECG) examinations. The ST-segment duration, QT interval, and ST/QT ratio were compared among the groups, while the diagnostic sensitivity and specificity of ST-segment duration and ST/QT for distinguishing HCM from HVH were assessed. Results  Statistically significant differences were observed in ST-segment duration and ST/QT among the three groups (both P<0.01). Compared with the control group, both HCM and HVH groups exhibited significantly elevated ST-segment duration and ST/QT ratio (both P<0.01), while no statistically significant difference was found in the QT interval. Diagnostic efficiency evaluation revealed that the sensitivity of ST-segment duration and ST/QT for diagnosing HCM was 77.27% and 86.36%, respectively, with specificity of 86.67% and 77.78%, and AUC values of 0.847 (P<0.01) and 0.859 (P<0.01). For diagnosing HVH, the sensitivity of ST-segment duration and ST/QT was 64.52% and 70.97%, respectively, with specificity of 97.78% and 93.33%, and AUC values of 0.833 (P<0.01) and 0.849 (P<0.01), respectively. Conclusion  Both ST-segment duration and ST/QT could serve as diagnostic indicators for HCM and HVH, with high specificity.

  • Effect of specialist health education combined with continuity of care on patients with dry eye syndrome after cataract surgery
    ZHANG Ying
    Practical Electrocardiology and Clinical Treatment. 2025, 34(6): 878-882. https://doi.org/10.13308/j.issn.2097-5716.2025.06.019
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    Objective  To investigate the intervention effect of specialist health education combined with continuity of care on patients with dry eye syndrome after cataract surgery. Methods  One hundred patients with dry eye syndrome after cataract surgery were randomly divided into an observation group and a control group using a random number table method, with 50 cases in each group. The observation group received a combined intervention model of specialist health education and continuity of care, while the control group received routine nursing care. The improvement in visual acuity (measured by the logMAR chart), tear film stability, self-care ability, and occurrence of complications were compared between the two groups. Results  After the intervention, the observation group showed better visual acuity compared to the control group ［(0.12±0.05) vs. (0.25±0.08), P<0.05］. Furthermore, all tear film stability indicators and self-care ability scores in the observation group were all significantly better than those in the control group, while the incidence of complications was significantly lower; all the differences between the two groups were statistically significant (all P<0.05). Conclusion  The combined nursing model could effectively promote the recovery of patients' visual acuity, enhance tear film stability, improve their selfcare ability, and reduce the incidence of complications.
  • Efficacy analysis of second-generation cryoballoon ablation for non-valvular paroxysmal atrial fibrillation
    ZHOU Ye, ZHEN Ya, ZHONG Wei, CHEN Rui, DAI Zhiyin, YUAN Wei
    Practical Electrocardiology and Clinical Treatment. 2025, 34(6): 799-804. https://doi.org/10.13308/j.issn.2097-5716.2025.06.004
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    Objective  To evaluate the safety and efficacy of the Medtronic second-generation cryoballoon ablation (CBA) in treating non-valvular paroxysmal atrial fibrillation (PAF). Methods  Sixty-five patients with non-valvular PAF who had not previously undergone pulmonary vein isolation (PVI) were enrolled. All patients were treated by using the Medtronic second-generation cryoballoon ablation system. Baseline data, procedure-related parameters, and 12-month follow-up results were collected. Based on whether atrial fibrillation recurred, these patients were divided into a non-recurrence group and a recurrence group. General clinical data, immediate procedural success rate, intraoperative parameters, and procedure-related complications were compared between the two groups. Results  All 65 patients successfully achieved circumferential PVI solely through CBA, with an immediate procedural success rate of 100%. The atrial fibrillation ablation success rate at 12-month follow-up was 908%. The mean procedure time was (98.68±19.13) min. The overall incidence of intraoperative and postoperative complications was 7.7%, with phrenic nerve injury occurring in 3.1% of cases. Conclusion  Second-generation CBA demonstrates high safety and efficacy in treating nonvalvular PAF, supporting its clinical utility for tailored therapeutic strategies.

  • Predictive value of electrocardiogram MVP score in hypertension complicated by atrial fibrillation
    WENG Yanqin, WANG Xinkang
    Practical Electrocardiology and Clinical Treatment. 2026, 35(1): 41-44. https://doi.org/10.13308/j.issn.2097-5716.xd20250320
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    Objective  To investigate the predictive value of electrocardiogram morphology-voltage-P-wave duration (MVP) score in hypertension complicated by atrial fibrillation (AF). Methods  A total of 198 hospitalized patients with hypertension were enrolled, and divided into an AF group (n=99) and a hypertension-only group (n=99) based on the presence of paroxysmal AF. Indicators such as left atrial diameter (LAD), left ventricular end-diastolic diameter (LVEDD), LVEF, P-wave duration, P-wave voltage in lead Ⅰ, MVP score, PtfV1, RV5, and RV5+SV1 were compared between the two groups. The predictive efficacy of MVP score was analyzed using ROC curve analysis. Results  The LAD in the AF group was significantly larger than that in the hypertension-only group (P<0.001), while there were no statistically significant differences in LVEDD or LVEF between the two groups (both P>0.05). P-wave duration, positive rate of PtfV1, RV5, RV5+SV1, and MVP score were all significantly higher in the AF group, whereas the P-wave voltage in lead Ⅰ was significantly lower compared with the hypertension-only group (P<0.05). The area under the ROC curve for an MVP score≥4 points in predicting AF was 0.818, with a sensitivity of 0.838 and a specificity of 0.798. Conclusion  The MVP score is an independent predictor of AF in patients with hypertension.

  • Mendelian randomization analysis of causal relationship between gastroesophageal reflux disease and gallstone disease
    XU Feng, LI Jiajia, HE Bangyao, CHI Yu
    Practical Electrocardiology and Clinical Treatment. 2026, 35(1): 65-71. https://doi.org/10.13308/j.issn.2097-5716.xd20250251
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    Objective  To explore the bidirectional causal relationship between gastroesophageal reflux disease (GERD) and gallstone disease using Mendelian randomization (MR) approach. Methods  Instrumental variables—single nucleotide polymorphisms (SNPs)—were obtained from public Genome-Wide Association Study (GWAS) databases, and two-sample bidirectional MR analyses were performed mainly by the inverse variance weighted (IVW) method. MR-PRESSO test, Cochran's Q test, MR-Egger regression intercept test, and leave-one-out analysis were used for sensitivity analysis to assess the reliability and stability of the study results. Subsequently, MR analysis was repeated after adjusting for the effects of different confounding factors to validate the results. The GERD data were sourced from the IEU OpenGWAS project, comprising a total of 602 604 samples (129 080 cases and 473 524 controls). The gallstone disease data were obtained from the FinnGen Biobank, comprising a total of 214 167 samples (19 023 cases and 195 144 controls). ResultsThe results by using the IVW method indicated a causal effect of GERD on gallstone disease (OR=1.472, 95%CI: 1.326-1.634, P=3.688×10－13), and also a causal effect of gallstone disease on GERD (OR=1.048, 95%CI: 1.027-1.069, P=5.791×10－6). After adjusting for confounding factors, the results by IVW method showed that the positive association risk of GERD on gallstone disease still remained (OR=1.407, 95%CI: 1.211-1.635, P=7.948×10－6), and the positive association risk of gallstone disease on GERD also remained (OR=1.052, 95%CI: 1.029-1.075, P=3.316×10－6). The analysis results using MR-Egger regression intercept test results indicated no evidence of horizontal pleiotropy among the included instrumental variables. The results by leave-one-out analysis suggested that no single SNP that could significantly affect the results. Conclusion  MR analysis supports a bidirectional causal relationship between GERD and gallstone disease.

  • Application value of wearable electrocardiogram devices in monitoring post-PCI cardiac risk among patients with coronary heart disease
    YIN Tingting, YANG Long, MEN Li, LIU Wanping, TANG Shuqin, WANG Xiao, FAN Ping
    Practical Electrocardiology and Clinical Treatment. 2025, 34(5): 625-630. https://doi.org/10.13308/j.issn.2097-5716.2025.05.001
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    Objective To assess the feasibility and application value of wearable electrocardiogram (ECG) devices in the remote dynamic monitoring of ECG abnormalities among patients with coronary heart disease (CHD) after percutaneous coronary intervention (PCI), and to explore the dynamic change characteristics and clinical significance of various kinds of arrhythmias. Methods A total of 124 CHD patients after PCI from three primary hospitals separately in Kuche City, Shawan City, and Shache County of Xinjiang Uygur Autonomous Region were enrolled. Village doctors were trained to assist patients in wearing wearable ECG devices, and a 12-lead resting ECG was recorded weekly for these patients one month after discharge. Basic clinical information during hospitalization and ECG data for four consecutive weeks after discharge were collected. Line charts were plotted, and the Cochran-Armitage trend test was used to analyze the changes in the detection rates of various kinds of arrhythmias monitored by the wearable devices over the four weeks. Results During the one-month continuous dynamic monitoring, the wearable ECG devices demonstrated high capabilities in detecting various kinds of arrhythmias, including rhythm abnormalities (41 cases, 33.06%), conduction blocks (29 cases, 23.39%), ST-segment changes (71 cases, 57.26%), electrical axis deviation (18 cases, 14.52%), ventricular hypertrophy (8 cases, 6.54%), and QT interval abnormalities (88 cases, 70.97%). The cumulative detection rate of rhythm abnormalities, ST-segment changes, electrical axis deviation, ventricular hypertrophy, and QT interval abnormalities all showed a weekly increasing trend (Cochran-Armitage trend test P<0.05). Some patients experienced the same type of arrhythmia multiple times during the follow-up, suggesting that electrophysiological abnormalities exhibited dynamic fluctuations or a persistent state. Conclusion Wearable ECG devices could effectively achieve remote dynamic ECG monitoring for post-PCI patients, with good feasibility and clinical utility.
  • Analysis of risk factors for new-onset atrial fibrillation in patients with septic shock
    TANG Wenjuan, ZHANG Baowei
    Practical Electrocardiology and Clinical Treatment. 2025, 34(6): 805-810. https://doi.org/10.13308/j.issn.2097-5716.2025.06.005
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    Objective  To investigate the risk factors for new-onset atrial fibrillation (AF) in patients with septic shock, and their impact on prognosis. Methods  A total of 302 patients with septic shock were retrospectively enrolled, and divided into an AF group and a control group based on the occurrence of new-onset AF. Baseline characteristics were compared between the two groups. Univariate and multivariate Logistic regression analyses were used to identify independent risk factors for new-onset AF. Propensity score matching (PSM) analysis was employed to assess the impact of new-onset AF on the prognosis of patients. Results  During hospitalization, 57 patients developed new-onset AF. Compared with the control group, patients in the AF group were older, with a larger left atrial diameter, and lower left ventricular ejection fraction. Multivariate Logistic regression analysis identified age, left atrial diameter, and electrolyte disturbances as independent risk factors for new-onset AF in patients with septic shock. PSM analysis revealed that patients in the AF group had significantly prolonged ICU length of stay, although there was no statistically significant difference in in-hospital mortality between the two groups. Conclusion  The incidence of new-onset AF is high in patients with septic shock, and it significantly prolongs ICU length of stay. Age, enlargement of left atrial diameter, and electrolyte disturbances serve as independent risk factors for new-onset AF, providing a basis for early risk stratification and targeted intervention.