Abstract：Objective To explore the changes of heart rate variability (HRV) in patients with type 2 diabetes and pre-diabetes. Methods We selected 58 patients diagnosed with type 2 diabetes (diabetes group), 40 patients with prediabetes (prediabetes group), and 61 healthy physical examinees (control group). Each HRV index of the diabetes and prediabetes groups was compared with that of the control group. Results The values of SDNN, SDANN, rMSSD, PNN50, HF, LF and LF/HF in the diabetes group were separately (96.27±16.32) ms, (86.40±15.66) ms, (25.47±4.02) ms, (4.47±1.18)%, 127.86±30.30, 242.03±65.39 and 1.99±0.16; the values of the above HRV indexes in the prediabetes group were separately (100.90±13.28) ms, (91.88±12.20) ms, (26.23±3.68) ms, (4.61±0.87)%, 133.90±19.15, 265.68±39.64 and 1.94±0.16. In the patients with diabetes and pre-diabetes, SDNN, SDANN, rMSSD, PNN50, LF and HF all decreased to varying degrees compared with healthy people (P<0.05) while there was no significant change in LF/HF. Conclusion HRV changes occur not only in type 2 diabetes but also in the population with pre-diabetes. Early monitoring of HRV indexes helps to make early detection and diagnosis of cardiovascular autonomic neuropathy.
尹冰，黄艺，王毅芳. 2型糖尿病及糖尿病前期患者心率变异性分析[J]. 实用心电学杂志, 2024, 33(1): 49-52.
YIN Bing, HUANG Yi, WANG Yifang. Analysis of heart rate variability in patients with type 2 diabetes and pre-diabetes. JOURNAL OF PRACTICAL ELECTROCARDIOLOGY, 2024, 33(1): 49-52.
