Abstract：Objective To investigate the relationship between the occurrence of idiopathic premature ventricular contraction (IPVC) and the mechanism of autonomic nerve. Methods In a singlecenter retrospective study approach, we selected 156 patients with IPVC \[PVC group,with ≥10 000 times of PVCs per day recorded by 24hour ambulatory electrocardiography (AECG) or PVC burden≥10%\], and 84 physical examination subjects during the same period (control group) as research subjects. According to the 24-hour AECG examination results, the following heart rate variability indexes were calculated, including rMSSD, pNN50, HF, HFnorm and LF/HF. We compared the autonomic nervous tension between the two groups, and analyzed the relationship between PVC burden and changes of autonomic nervous tension. Results The indexes of rMSSD, pNN50, HF and HFnorm in the PVC group are all significantly higher than those in the control group (P<0.01) while LF/HF is significantly lower (P<0.01). In the PVC group, the 24-hour PVC burden is positively correlated with rMSSD, pNN50 and HF (correlation coefficient r=0.492, 0.425 and 0.372, respectively; P<0.01) while it is negatively correlated with LF/HF (r=－0.206, P<0.05). Hourly PVC burden is positively correlated with hourly HFnorm in 28.8% (45/156) of the enrolled IPVC patients, and it is positively correlated with hourly LF/HF in 16.0%(25/156) of IPVC patients. Among 53.8% (84/156) of IPVC patients, hourly PVC burden is correlated with neither hourly HFnorm nor hourly LF/HF. ConclusionIn parts of patients, the occurrence of IPVC is associated with the changes of sympathetic and (or) parasympathetic nervous tension.
王晓飞，邹操，杜小娇，胡铭晟，林佳，孙世坤，薛枫，陈弹，李勋. 特发性室性早搏与自主神经张力的关系[J]. 实用心电学杂志, 2021, 30(5): 346-350.
WANG Xiaofei, ZOU Cao, DU Xiaojiao, HU Mingsheng, LIN Jia, SUN Shikun, XUE Feng, CHEN Tan, LI Xun. Relationship between occurrence of idiopathic premature ventricular contraction and autonomic nervous tension. JOURNAL OF PRACTICAL ELECTROCARDIOLOGY, 2021, 30(5): 346-350.
