Abstract:ST-segment changes serve as primary clinical indicators for assessing myocardial ischemia at present. However, owing to their relatively low sensitivity, parts of patients with acute coronary syndrome may be missed diagnosed. Several other ECG markers could be equated with ST-segment changes in the evaluation of myocardial ischemia with earlier occurrence time. These ECG markers include ischemic J waves, terminal QRS distortion, U-wave inversion, chest lead T-wave imbalance, isolated TaVL wave inversion, and ST-segment prolongation. However, they are often ignored clinically because of being lack of comprehensive understandings. This paper presents case analyses involving these equivalent indicators, which is aimed to attract clinical attention.