Abstract:Objective To evaluate the application value of electrocardiogram(ECG) in diagnosing anomalous origin of left coronary artery from pulmonary artery(ALCAPA). Methods Sixteen ALCAPA patients were enrolled in our study who had admitted in Wuhan Asia Heart Hospital from December 2004 to September 2016. They were diagnosed with ALCAPA by dual source computed tomography and confirmed by surgery. Theses patients were classified into group A(<12 months, 4 cases) and group B(>12 months, 12 cases), and their clinical manifestations and ECG features were analyzed. Results Crying and hard sucking were mainly observed among infants in group A while chest pain and backache were primary symptoms of group B. Patients in both of the two groups could be heard cardiac souffle in the apex of heart and between the fourth rib of the edge of left sternum. The incidences of abnormal Q wave and ST-T change in lead Ⅰ and aVL were both high in the two groups, with no statistically significant differences(P>0.05). However, the incidence of T wave inversion in lead V5and V6 in group A was significantly higher than that in group B, with statistically significant difference(P<0.05). Conclusion ECG of ALCAPA is characterized by abnormal Q wave complicating ST-T changes in lead Ⅰ and aVL. T wave inversion in lead V5 and V6 indicates serious myocardial ischemia among infants under 12 months. A combination of characteristic changes of ECG and physical examination is helpful for the diagnosis of ALCAPA.
吕航, 刘鸣, 库雷志, 李炜. 心电图诊断左冠状动脉异常起源于肺动脉的应用价值[J]. 实用心电学杂志, 2017, 26(2): 119-123.
吕Hang , LIU Ming, KU Lei-Zhi, LI Wei. Application value of electrocardiogram in diagnosing anomalous origin of left coronary artery from pulmonary artery. JOURNAL OF PRACTICAL ELECTROCARDIOLOGY, 2017, 26(2): 119-123.
[1] DodgeKhatami A, Mavroudis C, Backer CL. Anomalous origin of the left coronary artery from the pulmonary artery: collective review of surgical therapy[J]. Ann Thorac Surg, 2002, 74(3):946-955.[2] Arciniegas E, Farooki ZQ, Hakimi M, et al. Management of anomalous left coronary artery from the pulmonary artery[J]. Circulation, 1980, 62(2Pt2):I180-I189.[3] Bland EF, White PD, Garland J. Congenital anomalies of coronary arteries: report of unusual case associated with cardiac hypertrophy[J]. Am Heart J, 1933, 8(6):787-801.[4] Chang RR, Allada V. Electrocardiographic and echocardiographic features that distinguish anomalous origin of the left coronary artery from pulmonary artery from idiopathic dilated cardiomyopathy[J]. Pediatr Cardiol, 2001, 22(1):3-10.[5] Wesselhoeft H, Fawcett JS, Johnson AL. Anomalous origin of the left coronary artery from the pulmonary trunk. Its clinical spectrum, pathology, and pathophysiology, based on a review of 140 cases with seven further cases[J]. Circulation, 1968, 38(2):403-425.[6] Johnsrude CL, Perry JC, Cecchin F, et al. Differentiating anomalous left main coronary artery originating from the pulmonary artery in infants from myocarditis and dilated cardiomyopathy by electrocardiogram[J]. Am J Cardiol, 1995, 75(1):71-74. [7] Lee ML, Chiu IS, Chen SJ, et al. Imaging characteristics of anomalous left coronary artery from the pulmonary artery[J]. J Thorac Imaging, 2002, 17(1):96-100.[8] Cramer JW, Cinquegrani M, Cohen SB. Takeuchi repair of anomalous left coronary artery from the pulmonary artery[J]. J Cardiovasc Comput Tomogr, 2015, 9(5):457-458.