摘要 目的 探讨服用曲美他嗪对冠心病行冠脉内支架置入术后患者生活质量的改善作用。方法 将72例接受冠状动脉支架置入的患者随机分为两组，治疗组患者持续服用曲美他嗪联合冠心病基本药物；对照组仅接受冠心病基本药物治疗。术前及术后一年，利用健康调查简表(the MOS item short from health survey,SF36)进行问卷调查。结果 术前两组患者SF36量表各项基础数值比较，差异无统计学意义（P>0.05）；术后一年，SF36量表中的生理功能、躯体疼痛、总体健康、活力、社会能力指标比较，差异有统计学意义（P<0.05）。结论 服用曲美他嗪可提高冠状动脉支架置入术后冠心病患者的生活质量。
Abstract：Objective To investigate the effect of trimetazidine in improving the life quality of patients with coronary disease after coronary stent implantation. Methods Seventytwo patients implanted with coronary stent were randomly divided into two groups: treatment group and control group. Patients in the treatment group took trimetazidine combined with essential drugs of coronary heart disease persistently while the ones in the control group only accepted therapy with essential drugs. Before the operation one year later, questionnaire survey was performed with the MOS item short from health survey(SF-36). Results In terms of each basic value in SF-36 health survey table, there was no statistically significant difference between the two groups before the implantation(P＞0.05). One year after the operation, there were statistically significant differences in the indices of physiological functions, physical pain, overall health, vitality and social ability in SF-36 health survey table(P＜0.05). Conclusion Taking trimetazidine can improve the life quality of patients with coronary heart disease after coronary stent implantation.
袁伟, 张玮, 李小荣, 曹克将. 曲美他嗪改善冠状动脉支架置入术后患者生活质量的临床研究[J]. 实用心电学杂志, 2016, 25(5): 346-348.
YUAN Wei, ZHANG Wei, LI Xiao-Rong, CAO Ke-Jiang. Clinical study of trimetazidine in improving the life quality of patients after coronary stent implantation. JOURNAL OF PRACTICAL ELECTROCARDIOLOGY, 2016, 25(5): 346-348.
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2016, Vol. 25 
