卡托普利辅治对病毒性心肌炎患儿血清肌钙蛋白I、心电图及心功能的影响

侯艳芳

实用心电与临床诊疗 ›› 2018, Vol. 27 ›› Issue (2) : 116-118.

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实用心电与临床诊疗 ›› 2018, Vol. 27 ›› Issue (2) : 116-118. DOI: 10.13308/j.issn.2095-9354.2018.02.009
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卡托普利辅治对病毒性心肌炎患儿血清肌钙蛋白I、心电图及心功能的影响

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Influence of adjunctive therapy of captopril on serum cardiac troponin I, ECG and cardiac function among children with viral myocarditis

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摘要

目的  观察卡托普利辅治对病毒性心肌炎患儿血清肌钙蛋白I(cardiac troponin I,cTnI)、心电图及心功能的影响。方法  将2016年11月至2017年10月我院治疗的148例病毒性心肌炎患儿作为研究对象,将其依据随机数表法分为两组,各74例。对照组采取常规综合疗法治疗,观察组加用卡托普利治疗。观察两组治疗前后cTnI水平、心电图及心功能变化情况。结果  治疗前两组心律失常、ST-T改变发生率、cTnI水平、左室射血分数(left ventricular ejection fraction,LVEF)对比,差异无统计学意义(P>0.05);治疗后观察组心律失常、ST-T改变发生率与cTnI水平均低于对照组,LVEF高于对照组,差异有统计学意义(P<0.05)。结论  卡托普利辅治病毒性心肌炎效果确切,有利于调节机体cTnI水平,减少心电图异常现象,增强患儿心功能。

Abstract

Objective  To observe the influence of adjunctive therapy of captopril on cardiac troponin Ⅰ(cTnI), ECG and cardiac function among the children with viral myocarditis. Methods  We selected 148 viral myocarditis children as research objects who had been treated in our hospital from November 2016 to October 2017. They were divided into two groups each with 74 cases in random number table method. The conventional combined treatment was applied in the control group while captopril was added to the observation group. The level of cTnI, ECG and cardiac function before and after therapy were observed and compared between the two groups. Results  Before the treatment, the incidence rates of arrhythmia and ST-T change, the level of cTnI, and left ventricular ejection fraction(LVEF) did not vary significantly between the two groups(P>0.05). After the therapy, the incidence rates of arrhythmia and ST-T change, and cTnI level in the observation group were all significantly lower than those in the control group while LVEF was higher, with statistically significant differences(P<0.05). Conclusion  The adjunctive therapy of captopril for viral myocarditis is effective, which helps to modulate the cTnI level of the organism, reduce ECG abnormalities and enhance viral myocarditis children’s cardiac function.

关键词

病毒性心肌炎 / 卡托普利 / 血清肌钙蛋白 / 心电图 / 心功能

Key words

viral myocarditis / captopril / serum troponin / electrocardiogram / cardiac function

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侯艳芳. 卡托普利辅治对病毒性心肌炎患儿血清肌钙蛋白I、心电图及心功能的影响[J]. 实用心电学杂志, 2018, 27(2): 116-118 https://doi.org/10.13308/j.issn.2095-9354.2018.02.009
HOU Yan-Fang. Influence of adjunctive therapy of captopril on serum cardiac troponin I, ECG and cardiac function among children with viral myocarditis[J]. JOURNAL OF PRACTICAL ELECTROCARDIOLOGY, 2018, 27(2): 116-118 https://doi.org/10.13308/j.issn.2095-9354.2018.02.009

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