Abstract：Objective To investigate the change regulation of heart rate variability(HRV) in patients with abnormalities in sleep apnea monitoring, and thus to evaluate the cardiovascular function and predict the incidence of cardiovascular events. Methods A total of 136 patients with different degrees of sleep snoring were synchronously carried out polysomnography(PSG) testing and ambulatory electrocardiography(AECG) monitoring. Ninetyseven ones diagnosed as having sleep apnea syndrome(SAS) were screened out of those patients, namely SAS group, and then were divided into three subgroups—mild, moderate and severe subgroups according to apnea hypopnea index. The other 39 patients were served as control group. With the help of the second generation of SAS screening technology by DMS company, we analyzed the monitored respiratory waveforms, time domain HRV indexes(SDNN, rMSSD, PNN50) and frequency domain HRV indexes(LF, HF). Results The 24hour SDNN, rMSSD, PNN50 and HF in the SAS group were all significantly lower than those in the control group, with statistically significant differences(P<0.05). LF values of patients in the moderate and severe SAS subgroups in sleep were both significantly higher than those in the control group, with statistically significant differences(P<0.05). Conclusion The severer SAS detected by PSG and AECG is, the lower the values of SDNN, rMSSD, PNN50 and HF indexes will be, bringing more significant hypofunction of vagus nerve and higher risk of cardiovascular events caused by increased sympathetic nerve tension.
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2017, Vol. 26 
