Abstract:Cardiac implantable devices are widely used in clinical practice. However, traditional transvenous pacemakers are associated with a series of complications such as infection due to the presence of leads and pockets. Leadless cardiac implantable devices, without leads or pockets, obtain unique advantages among the populations at high risk of infection. This article mainly provides an overview of the ventricular pacing function, atrioventricular synchronization function and defibrillation function of leadless pacemakers, and attempts at ventricular resynchronization therapy based on the existing clinical evidences and clinical applications at present. It also reviews the advantages and disadvantages of the devices, and current clinical recommendations.