Abstract：Objective To observe the characteristics of essential hypertension(EH) patients with premature ventricular contraction ( PVC), and provide references for clinical treatment. Methods Two hundred EH patients who had undergone Holter and ambulatory blood pressure monitoring during hospitalization were selected. The relationship between PVC, and 24 h blood pressure, changes of blood pressure circadian rhythm, left ventricular hypertrophy, myocardial ischemia and cardiac function was observed. Results (ⅰ) There is no statistical difference of 24 h blood pressure between EH patients with and without PVC. In the patients with Lown classification grade 3 and above, the 24 h average systolic blood pressure (SBP), and day and night average SBP are all higher than those in the hypertensives below grade 3. (ⅱ) Among the patients with myocardial ischemia or left ventricular hypertrophy, the total incidence of PVC, and the incidence of PVC Lown classification grading 3 and above are both higher than those in the patients without myocardial ischemia or left ventricular hypertrophy.(ⅲ) Among the patients complicating heart failure, the total incidence of PVC, and the incidence of PVC Lown classification grading 3 and above are both higher than those in the patients without heart failure. In the heart failure patients with NYHA cardiac function classification of Ⅲ and above, the total incidence of PVC, and the incidence of PVC Lown classification grading 3 and above are both higher than those in the patients below NYHA classification of Ⅲ. Conclusion In EH patients, weakened or disappeared circadian rhythm of blood pressure, and complication of left ventricular hypertrophy or myocardial ischemia and heart failure, the incidence and complexity of PVC increase.
