Abstract:Currently, cryoballoon ablation has been a new technique for treating atrial fibrillation. A large number of clinical researches have confirmed its efficacy and safety in the treatment of atrial fibrillation, but there is still a relatively high incidence of silent cerebral embolism. Although several studies have suggested that silent cerebral embolism has a slight impact on the nervous system, however, some studies have also found that it can affect the function of speech and memory. Some scholars even believe that silent cerebral embolism may have longterm adverse effects on the nervous system. In this review, the effects of cryoballoon ablation on the occurrence of silent cerebal embolism are discussed from the aspects of pathogenesis, risk factors, clinical manifestations, prevention and treatment strategies.