Abstract：Objective Based on the ischemia classification according to the change of QRS complex in ECG of patients with acute ST segment elevation myocardial infarction(STEMI), to explore the relationship between electrocardiographic ischemia and serum hscTnI. Methods According to their ECGs on admission, 120 STEMI patients were divided into grade Ⅲ ischemia group(with QRS terminal distortion; n=81, accounting for 67.5%) and grade Ⅱis chemia group(without QRS terminal distortion; n=39, accounting for 32.5%). Coronary angiographic examination and hscTnI inspection were performed on both of the two groups. The relationship between the circumstances of coronary obstruction and serum hscTnI was compared between two groups. Results (i) In grade Ⅲ ischemia group, there were 68 males(83.95%) and 13 females(16.05%); in grade Ⅱ ischemia group, there were 27 males(69.23%) and 12 females(30.77%). There was statistically significant difference in sex between the two groups(P<0.05). (ii) The incidence of lesion in left anterior descending artery among patients of grade Ⅲ ischemia group was higher than that in the other group(P＜0.05), however, the incidence of lesion in left circumflex artery was lower(P<0.001). (iii) The measured serum hscTnI was characterized by skew distribution with statistically significant difference(Z=-2.78, P<0.006). (iv) Compared two groups of patients with hs-cTnT level , grade II ischemia is lower than the levels grade III ischemia, the difference was statistically significant（P<0.05）. Conclusion Grade Ⅲ ischemia in ECG of STEMI patients is associated with the concentration of serum hs-cTnI.
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2017, Vol. 26 
