Abstract：ObjectiveTo study the relationship between high sensitive C-reactive protein(Hs-CRP) and stability of coronary artery atheromatous plaque. Methods Sixtyseven coronary heart disease patients who were cured between October 2007and January 2008 in our hospital were enrolled. The average age of the patients was （59.48±5.70）years old, among which 43 were males and 24 were females. There were 23 stable angina pectoris patients, 22 unstable angina pectoris patients and 22 acute myocardial infarction patients among them. Twenty paroxysmal supraventricular tachycardia patients who were cured during the same time in our hospital without structural heart disease(but with good heart function) were enrolled as control group, the average age of the patients was （44.35±5.41）years old, among which 10 were males and 10 were females. To detect the Hs-CRP content, take venous blood in next morning with empty stomach.Results Hs-CRP content of SA, UA and AMI groups patients were more than control group (P<0.01). Hs-CRP content of AMI group significantly increased, which was significantly higher than SA and UA group. There was no signiicant difference between SA and UA group. Conclusion Hs-CRP has relationship with stability of coronary artery atheromatous plaque. To detect Hs-CRP contents of ACS patients have clinical significance for evaluation of therapeutic effect and prognosis.
2012, Vol. 21 
