Abstract:Long-QT syndrome(LQTS) is characterized by prolongation of ventricular repolarization time, and increase of inhomogeneity and dispersion. LQTS is dangerous because it may lead to torsade de pointes(TdP) and ventricular fibrillation. The clinical manifestations include syncope, tetany or sudden death. LQTS includes congenital longQT syndrome(cLQTS) and acquired long-QT syndrome(aLQTS). The latter is more frequently seen in clinical practice than the former, and is potentially lethal, which makes it one of the most important reasons for sudden cardiac death in hospital. In the calculation of QT/QTc intervals, to evaluate ventricular repolarization as accurately as possible in different methods within the recommended range of critical value of QT/QTc interval prolongation time can predict the occurrence of TdP and further reduce the rate of sudden death.
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