Abstract：Objective: To access the affects of realtime glucose monitoring system on blood glucose control and mortality in critically craniocerebral trauma patients with hyperglycemia in intensive care unit (ICU). Methods: One hundred and seventeen ICU critical craniocerebral trauma patients with hyperglycemia were studied by RT-CGMS（n=59） and fingertip blood monitoring group (GM group, n=58), and both were worn by RT-CGMS for 72 h(GM group blinded RT-CGMS).Hypoglycemia incidence were observed in the two groups, as well as days in ICU and 30-d mortality. Results: The glucose variability and hypoglycemia incidence in RT-CGMS group were significantly lower than the fingertip blood group，with less days in ICU and 30-d mortality(P< 0.05). Conclusion: RT-CGMS can assist in the smooth control of blood glucose, and reduce the adverse events of hypoglycemia. By optimizing glycemic control, reducing the mortality of hyperglycemia in critically craniocerebral trauma patients.
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