糖化血红蛋白检测在早期心肌损伤诊断中的价值

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江苏大学学报（医学版） ›› 2012, Vol. 22 ›› Issue (6) : 491-493.

检验医学

糖化血红蛋白检测在早期心肌损伤诊断中的价值

李礼1，于正清1，胡娟玉2，陈玮1，赵广春1，张似锦1，钱雷1

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Value of detecting the glycosylated hemoglobin in early myocardial injury

LI Li1, YU Zhengqing1, HU Juan-yu2, CHEN Wei1, ZHAO Guang-chun1, ZHANG Si-jin1, QIAN Lei1

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摘要

目的：探讨糖化血红蛋白A1c（HbA1c）水平对早期心肌损伤诊断的临床价值以及HbA1c与超敏肌钙蛋白T（hs-cTnT）的相关性。方法：选取397例早期心肌损伤患者检测其HbA1c，根据HbA1c水平分为HbA1c＜5.7%、5.7～6.4%、≥6.5% 3组，同时测定hs-cTnT，并作比较。结果： HbA1c≥6.5%组的hs-cTnT水平明显高于其他两组（P＜0.05），HbA1c水平与hs-cTnT呈正相关（r＝0.952 9，P＜0.05）。结论：高HbA1c是心肌损伤的独立危险因素，与hs-cTnT呈正相关。

Abstract

Objective: To explore the value of detection of glycosylated hemoglobin A1c(HbA1c) for the patients with early myocardial injury and investigate the correlation between HbA1c and highsensitivity cardiac troponin T(hscTnT). Methods： HbA1c was measured in 397 subjects with early myocardial injury, according to level of HbA1c, patients were divided into HbA1c＜5.7% group, 5.7%-6.4% group and ≥6.5% group, at the same time , hscTnT were determined. Results： hscTnT level in HbA1c≥6.5% group was significantly higher than in HbA1c＜5.7% group and 5.7%-6.4% group（P＜0.05）, HbA1c level was significantly positive correlated with hscTnT（r＝0.952 9，P＜0.05）. Conclusion： Higher HbA1c is the independent risk factor of myocardial injury and HbA1c was positive correlated with hscTnT.

关键词

糖化血红蛋白 / 肌钙蛋白 / 心肌损伤

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李礼1，于正清1，胡娟玉2，陈玮1，赵广春1，张似锦1，钱雷1. 糖化血红蛋白检测在早期心肌损伤诊断中的价值[J]. 江苏大学学报（医学版）, 2012, 22(6): 491-493

LI Li1, YU Zhengqing1, HU Juan-yu2, CHEN Wei1, ZHAO Guang-chun1, ZHANG Si-jin1, QIAN Lei1. Value of detecting the glycosylated hemoglobin in early myocardial injury[J]. Journal of Jiangsu University(Medicine Edition), 2012, 22(6): 491-493

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