Abstract：［Abstract］Objective： To comprehend the contributions of Gram stain classification and different strength of antibioticresistance of clinical pathogenic bacteria to the levels of procalcitonin（PCT）in bacteria infected patients，and to analyze the correlations between PCT and Creactive protein（CRP）in several groups of bacteria infected patients. Methods：PCT and CRP were detected by circular enhanced fluorescence immunoassay (CEFA) and immunoturbidimetric assay. The selected patients were general antibioticresistant Acinetobacter Baumannii infected group(GRAB),extensively antibioticresistant Acinetobacter Baumannii infected group(ERAB),general antibioticresistant Staphylococcus Aureus infected group(GRSA),extensively antibioticresistant Staphylococcus Aureus infected group(ERSA). The healthy control group was also chosen. Kruskal Wallis H test (post hoc pairwise comparison with Nemenyi test)was used to statistically compare the levels of PCT and CRP among the three groups of Acinetobacter Baumannii infected group (AB), Staphylococcus Aureus infected group (SA) and the control group, and among the three groups of general antibioticresistant bacteria group (GR) , extensively antibioticresistant bacteria group (ER) and the control group .Spearman rho correlation analyses was used to evaluate the correlation between PCT and CRP . Results：PCT levels: there was no significant difference between Group AB and Group SA (P>0.05), and the two groups were higher than the control group (P all <0.05); there was no significant difference between Group GR and the control group (P>0.05), and two groups were lower than Group ER (P all <0.05). CRP levels: there was no significant difference between Group AB and Group SA (P>0.05), and the two groups were higher than the control group (P all<0.05); there was no significant difference between Group GR and Group ER(P>0.05), and the two groups were higher than the control group (P all<0.05).It was found that PCT positively correlated with CRP only in bacteria infected patients(P<0.05), but not in healthy people(P=0.952). Conclusion：General antibioticresistant bacteria infection may not prominently elevate the levels of PCT in patients. The bacteria with higher antibioticresistance may more strongly stimulate the expression of PCT in patients than the general antibioticresistant bacteria. Gramnegative bacteria infection stimulate the expression of PCT in patients may as the same as Grampositive bacteria in levels. There was positive correlation between PCT and CRP only in bacteria infected patients but not in healthy people.
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2016, Vol. 26 
