Abstract：Objective investigate the difference, advantages and disadvantages of atropine and isoproterenol in inducing supraventricular tachycardia. Methods Sixtyfive suspected patients with supraventricular tachycardia who were in our hospital from January 2010 to May 2015 underwent routine examination of transesophageal atrial pacing without any drug used. If supraventricular tachycardia failed to be induced, two drugs were separately used in the provocative test during different time periods. Among the 65 cases, 20 were randomly selected to be induced by isoproterenol(group A), and another 45 cases were induced by atropine(group B). The positive rates of these two drugs in provocative test were compared and analyzed. Results In the provocation process, various kinds of tachycardias were induced, including 19 cases of lowfast atrioventricular node reentrant tachycardia, 7 cases of orthodromic atrioventricular reentrant tachycardia, 3 cases of antidromic atrioventricular reentrant tachycardia, and 6 cases of reentrant atrial tachycardia. Another 4 cases of automatic atrial tachycardia and 6 cases of atrial fibrillation could voluntarily terminate themselves and thus they were not regarded as positive results. In the two groups, there were 35 positive cases in all, with 15 in group A, and 20 in group B. For the two drugs, the difference of positive rates in inducing tachycardia was statistically significant(P<0.05). Conclusion In inducing tachycardia during transesophageal atrial pacing, isoproterenol proved to be significantly more effective than atropine, which may be related to drug action. Atropine can not be repeatedly intravenously injected while isoproterenol can be repeatedly intravenously injected and control heart rate. Although isoproterenol is more safe, it has great impact on cardiac function.
许金兰. 阿托品和异丙肾上腺素对食管调搏诱发室上性心动过速效果对比[J]. 实用心电学杂志, 2015, 24(5): 330-332.
XU Jin-Lan. Comparison between the effects of atropine and isoproterenol in inducing supraventricular tachycardia during transesophageal atrial pacing. JOURNAL OF PRACTICAL ELECTROCARDIOLOGY, 2015, 24(5): 330-332.
2015, Vol. 24 
