Abstract：Atrioventricular nodal reentrant tachycardia(AVNRT) is the most common paroxysmal supraventricular tachycardia in clinical practice. At present, dual atrioventricular nodal pathways or multipathways are regarded as the matrix of AVNRT, but its exact physiopathologic mechanism and anatomical location have not been elucidated yet. The success rate of radiofrequency ablation can reach as high 95% among AVNRT patients in recent years. The molecular heterogeneity and distributional difference of ion channels may contribute to the formation of dual atrioventricular nodal pathways. In addition, the atrioventricular node is under the dual domination of the extracardiac and intracardiac autonomic nerves; imbalance of autonomic nervous system plays an important role in the induction and maintenance of AVNRT. This paper mainly introduces the research advances in the relationship among ion channels, autonomic nervous system and AVNRT.
朱云才，陈旸，李小平. 离子通道及自主神经系统与房室结折返性心动过速关系的研究进展[J]. 实用心电学杂志, 2021, 30(1): 8-12.
ZHU Yuncai, CHEN Yang, LI Xiaoping. Research progress on the relationship among ion channels, autonomic nervous system and atrioventricular nodal reentrant tachycardia. JOURNAL OF PRACTICAL ELECTROCARDIOLOGY, 2021, 30(1): 8-12.
