Abstract：Objective To explore the relationship between total ischemia burden(TIB) by ambulatory electrocardiography and coronary CT angiography(CTA) examination.MethodsOne hundred and four patients with symptoms of chest pain or risk factors for coronary heart disease underwent TIB and coronary CTA examination. The positive rates of TIB between coronary CTA positive group and negative group were compared and Spearman correlation test was carried out between the number of coronary lesions and TIB value. ResultsCompared with coronary CTA negative group, the positive rate of TIB in positive group was significantly increased(P<0.01) while the correlation coefficient between the number of coronary lesions and TIB value was 0.532(P<0.01) indicating a positive correlation.ConclusionThere is a significant correlation between TBI and coronary CTA examination. They reflect coronary heart disease in aspects of quantification of myocardial ischemia and degree of stenosis in coronary anatomy respectively and the combination of them are clinically valuable.
[1] Cohn PF. Total ischemic burden. Implications for prognosis and therapy[J]. Am J Med, 1989, 86(1):6-8.[2] 周志明，周玉杰，郭永和，等.动态心电图对无痛性心肌缺血的诊断价值[J].临床心血管病杂志，2008,24(5):355-356.[3] Zellweger MJ, Hachamovitch R, Kang X, et al. Prognostic relevance of symptoms versus objective evidence of coronary artery disease in diabetic patients[J]. Eur Heart J, 2006, 25(7):543-550.[4] 田玮，戚新玲.动态心电图监测60例心肌总缺血负荷的临床意义[J].实用心电学杂志，2004,13(4):246.[5] 中华放射学杂志心脏冠状动脉多排CT临床应用协作组.心脏冠状动脉多排CT临床应用专家共识[J].中华放射学杂志，2011,45(1):9-17.[6] Mark DB，Berman DS．Budoff MJ，et al. ACCF/ACR/AHA/NASCL/SAIP/SCAL/SCCT 2010 expert consensus document on coronary computed tomographic angiography：a report of the american college of cardiology foundation task force on expert consensus documents[J].Circulation，2010，121：2509-2543． ［7］ 胡建强，周炳炎，毛红娟，等．Holter评价冠心病心肌缺血的作用［J］．第二军医大学学报，2004，25(7):798-799．
2014, Vol. 23 
