Arrhythmia is one of the manifestation types of cardiotoxicity associated with antitumor therapies. In the presence of arrhythmia among patients with tumor, it is inevitable for the clinical treatment strategy of tumor and the outcome to be affected. Antitumorassociated arrhythmias has aroused more and more attention in clinicians. However, as one of the most commonlyseen arrhythmias in patients with tumor, sinus tachycardia is easily to be ignored in clinical practice. This paper reviews the mechanisms, diagnosis, evaluation and treatment of tumorassociated sinus tachycardia.