Abstract:Anthracyclines are widely used in various malignancies including breast cancer, sarcoma, leukemia and lymphoma. However, anthracyclines have attracted much attention because of their cardiotoxicity at present. Even at therapeutic doses, anthracyclines may also induce various types of arrhythmias including atrial fibrillation, supraventricular tachycardia, premature ventricular beats and ventricular tachycardia. Anthracyclines are independent risk factors for arrhythmias, which may be a marker of poor cardiovascular prognosis and clinical outcomes. Although the optimal treatment strategies for anthracyclinesrelated arrhythmias have not been found, it is essential for patients with a history of anthracyclines use to take standard and longterm ECG monitoring. Centering on anthracyclinesrelated arrhythmias, this paper reviews their types, epidemiology, mechanism, and treatment and management.
王玥莹,刘彤. 蒽环类药物相关心律失常研究进展[J]. 实用心电学杂志, 2022, 31(4): 238-242.
WANG Yueying, LIU Tong. Research advances in anthracyclinesrelated arrhythmias. JOURNAL OF PRACTICAL ELECTROCARDIOLOGY, 2022, 31(4): 238-242.