Abstract:Endocrine therapy slows down the tumor progression by interfering activation pathway of sex hormones. A variety of new breakthrough drugs improve the survival rates of patients with breast and prostate cancers. Sex hormones are the important factors that affect repolarization of ventricular cardiomyocytes(RVC), and highly associated with abnormal RVCinduced malignant arrhythmia. Specifically, it was reported that drugs used for endocrine therapy resulted in electrophysiological changes, including atrial fibrillation, QTc prolongation and torsade de pointes, increasing the mortality in patients with tumor. The paper summarizes the changes of electrocardiogram that induced by drugs used for endocrine therapy in patients with tumor.
耿旭红,王玥莹,马潇桐,潘烁. 肿瘤内分泌治疗对心电图的影响[J]. 实用心电学杂志, 2019, 28(6): 406-409.
Geng Xuhong, Wang Yueying, Ma Xiaotong,Pan Shuo. Effect of endocrine therapy on electrocardiogram in patients with tumor. JOURNAL OF PRACTICAL ELECTROCARDIOLOGY, 2019, 28(6): 406-409.