Abstract：Objective: To test the value of detection of heart type-fatty acid binding protein（H-FABP） on evaluating the patients with atrial fibrillation. Methods: H-FABP was measured in 196 healthy persons and 196 patients with atrial fibrillation by ELISA one-step sandwich assay，at the same time，creatine kinase isoenzyme-MB (CK-MB)and cardiac troponin I(cTnI) were determined． Results: The value of H-FABP in patients before treatment with atrial fibrillation，patients with atrial fibrillation after treatment，healthy persons were (2.8±1.3) μg/L，(2.3±1.4) μg/L，(1.6±1.1) μg/L；the value of cTnI were (0.26±0.05) μg/L，(0.23±0.06) μg/L，(0.05±0.02) μg/L；and the value of CK-MB were (12.8±3.6) U/L,(13.6±3.1) U/L,(12.1±2.7) U/L. There was significant difference in H-FABP level between patients before treatment，patients after treatment，healthy persons（P<0.05）. There was no significant difference in cTnI level between patients before treatment and patients after treatment (P>0.05). There was significant difference in cTnI level between patients with atrial fibrillation and healthy persons（P<0.05）. There was no significant difference in CK-MB level between patients before treatment，patients after treatment，healthy persons (P>0.05).Conclusion: Serum HFABP to patients with atrial fibrillation who tested have an important clinical value.
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2012, Vol. 22 
