Risk factors analysis associated with recurrence or metastasis of mediastinal lymph nodes in patients with type Ⅱ adenocarcinoma of esophageal and gastric junction after resection
HUANG Yong-gao, CHEN Xia, WANG Peng-cheng, JIA Wei-guang
（Department of Thoracic Surgery, the People′s Hospital of Taizhou, Taizhou Jiangsu 225300, China）
Abstract：Objective： To investigate risk factors of mediastinal lymph node metastasis or recurrence of type Ⅱ adenocarcinoma of esophagogastric junction(AEG) after radical resection. Method: We retrospectively analyzed the clinical data of 353 patients with type AEG Ⅱ who underwent radical resection (R0 resection) in our hospital. The risk factors of recurrence or metastasis of mediastinal lymph nodes were analyzed. Results: The overall rates of metastasis or recurrence of type Ⅱ AEG after operation was 12.5%(44/353). Univariate analysis showed that the histological grade, vascular invasion, N stage and distance from the esophagogastric junction(EGJ) to the proximal edge of primary tumor (≥2.5 cm) were the potential factors related to the metastasis or recurrence of the mediastinal lymph nodes after operation(P<0.05). Logistic multivariate regression analysis showed that distance from EGJ to the proximal edge of primary tumor (≥2.5 cm) and histological grade were independently related with the metastasis or recurrence of the mediastinal lymph nodes(P<0.05). Conclusions: The distance from the EGJ to the proximal edge of primary tumor (≥2.5 cm) and histological grade are independent factors of predicting the metastasis or recurrence of the mediastinal lymph nodes after R0 resection for type Ⅱ AEG.
收稿日期: 2016-03-30
作者简介: 黄永高（1973—），男，江西临川人，副主任医师，硕士，主要从事胸部肿瘤研究。
引用本文:
黄永高，陈霞，王鹏程，贾卫光. Ⅱ型食管胃连接处腺癌术后纵隔淋巴结复发或转移的相关因素分析[J]. 江苏大学学报:医学版, 2016, 26(05): 415-417,421.
HUANG Yong-gao, CHEN Xia, WANG Peng-cheng, JIA Wei-guang. Risk factors analysis associated with recurrence or metastasis of mediastinal lymph nodes in patients with type Ⅱ adenocarcinoma of esophageal and gastric junction after resection. Journal of Jiangsu University(Medicine Edition), 2016, 26(05): 415-417,421.
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2016, Vol. 26 
