Measurement and correlation of solubility for ginkgolic acid C15：1 in water
1.School of Food and Biological Engineering, Jiangsu University, Zhenjiang, Jiangsu 212013, China; 2.School of Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang, Jiangsu 212013, China; 3. School of Medical Science and Laboratory Medicine, Jiangsu University, Zhenjiang, Jiangsu 212013, China; 4.Dantu District Hospital, Zhenjiang, Jiangsu 212028, China
Abstract：The solubility of gingkgolic acid C15：1 in water was measured with solid-liquid equilibrium apparatus by fluorometry at temperature range from 288.15 to 313.15 K. The experimental data were correlated with models based on the Apelblat equation and ideal solution equation. The total average relative errors are 4.50％ and 2.44％, respectively. The results show that the solubility of ginkgolic acid C15：1 is increased with the increasing of temperature. Ideal solution equation and Apelblat equation of solubility are applicable for the specified temperature and solubility in the research. The simulated result of Apelblat equation is superior to that of ideal solution equation, and the predictive values are consistent with the experimental results. The values of entropy and enthalpy change of gingkgolic acid C15：1 in water are both positive according to van′t Hoff equtation, which indicates that the dissolve process of gingkgolic acid C15：1 in water is an endothermic process.
2015, Vol. 36 
