Abstract:The rise of the Third Industrial Revolution is reshaping the international economic structure and making a significant adjustment of the pattern of global industrial competition. Meanwhile, it is forming a historical intersection with the transformation of economic development mode of China and bringing great opportunities as well as severe challenges to Chinese economic development. Jiangsu, as one of the manufacturing provinces and vanguards of Chinese open economy, has its advantages to meet the Third Industrial Revolution. We should seize the historic opportunity brought by this revolution, accelerate the economic transformation and upgrading, and actively respond to the impact of the third industrial revolution.