Abstract：Objective To investigate the heart rate variability(HRV) and blood pressure variability(BPV) in patients with essential hypertension complicating acute cerebral infarction. Methods A total of 82 patients with essential hypertension complicating acute cerebral infarction and 108 patients with pure essential hypertension were enrolled in our study. Their ambulatory electrocardiography and ambulatory blood pressure were measured synchronously. Indices of HRV and BPV were calculated by computer automatically. Results Compared with pure essential hypertension group, the value of each HRV index was lower in cerebral infarction group, with statistically significant difference(P<0.05). In cerebral infarction group, the descending rate of nocturnal blood pressure was lower than that in pure essential hypertension group while the value of each BPV index was higher. And there were statistically significant differences(P<0.05) in the descending rate of nocturnal diastolic blood pressure, 24hour average systolic blood pressure(24 h SBP) and 24hour systolic blood pressure coefficient of variation(24 h SCV) between the two groups.Conclusion The autonomic nervous function of the patients with essential hypertension complicating acute cerebral infarction is significantly impaired if compared with the cases attacked by pure essential hypertension. It[LM]is clinically significant for evaluating severity and improving prognosis of hypertensives and those complicating acute cerebral infarction to make tracing observation on changes of HRV and BPV indices.
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2016, Vol. 25 
