高血压患者血压晨峰与心率变异性的相关性分析

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摘要目的探讨高血压患者血压晨峰与心率变异性（HRV）的相关性。方法对56例高血压患者行24 小时动态血压监测的同时行24小时动态心电图监测。根据血压晨峰情况分为两组:晨峰组（31例），血压晨峰为起床后2小时内平均收缩压与睡眠时最低平均收缩压（最低收缩压及其前后2次血压的平均值）之间的差值≥55 mmHg，其他为非晨峰组（25例）。分析24小时动态心电图计算机自动给出心率变异性参数的关系。结果晨峰组SDNN、SDANN、SDNN、PNN50与非晨峰组间差异有统计学意义。结论具有高血压晨峰现象的患者心率变异性偏低，提示交感、迷走神经功能平衡降低，心室肌电不稳定性增加。

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	刘斌
	林家弟
	陈序
	张弢
	李霞
	李露
	卜佳
	周咏梅

关键词 ：高血压, 血压晨峰, 心率变异性

Abstract：Objective To evaluate the relationship between morning blood pressure surge and heart rate variability（HRV）in the patients with hypertension. Methods Fifty-six patients with hypertension were performed by 24-hour ambulatory blood pressure monitoring. They were divided into with morning blood pressure surge group（31cases）and without morning blood pressure surge group（25 cases）according to the condition of 24-hour ambulatory blood pressure monitoring. The deviation of the average value in awaking 2 hours and the minimum value during sleep of the systolic blood pressure no less than 55 mmHg was defined as morning blood pressure surge. Their HRV time domain indexes were analyzed. Results The SDNN，SDANN，SDNN，PNN50 of morning blood pressure surge group were significantly higher than without morning blood pressure surge group. Conclusion The autonomic nerve function was damaged and electrophysiological instability of ventricular myocardium increased significantly in hypertension patients with morning blood pressure surge.

Key words：高血压血压晨峰心率变异性

引用本文:

刘斌, 林家弟, 陈序, 张弢, 李霞, 李露, 卜佳, 周咏梅. 高血压患者血压晨峰与心率变异性的相关性分析[J]. 实用心电学杂志, 2012, 21(3): 173-. LIU Bin, LIN Jia-Di, CHEN Xu, ZHANG Tao, LI Xia, LI Lu, BU Jia, ZHOU Yong-Mei. Analysis of the relationship between morning blood pressure surge and heart ratevariability in the patients with hypertension. JOURNAL OF PRACTICAL ELECTROCARDIOLOGY, 2012, 21(3): 173-.

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http://zzs.ujs.edu.cn/syxd/CN/ 或 http://zzs.ujs.edu.cn/syxd/CN/Y2012/V21/I3/173

［1］张维忠.血压变异和晨峰的概念及其临床意义［J］.中华心血管病杂志，2006，34（3）:287-288.

［2］William B，White MD. Importance of aggressive blood pressure lowering when it may matter most［J］. Am J Cardiol，2007，100（3A）: 101-161.

［3］宋越红，李建英，黄国秀.老年原发性高血压患者血压晨峰与心血管危险因素相关性研究［J］.临床心血管病杂志，2008，24（5）:366-368.

［4］Kario K， Pickering TG， Umeda Y， et al. Morning surge in blood pressure as a predictor of silent and clinical cerebrovascular disease in elderly hypertensive a prospective study［J］.Circulation，2003，107（10）:1401-1406.

［5］Gosse P， Cipriano C， Bemurat L， et al. Prognostic significance of blood pressure measured on rising［J］. J Hum Hypertens，2001，15（6）:413-417.

［6］Li Y，Thijs L，Hansen TW，Kikuya M，et al. Prognostic value of the morning blood pressure surge in 5645 subjects from 8 population［J］.Hypertension，2010，55（4）: 1040-1048.

［7］Leary AC，Struthers AD，Donnan PT，et al. The morning surge in blood pressure and heart rate is dependent on levels of physical activity after waking［J］. J Hypertens，2002，209（5）:865-870.

［8］齐连芬，胡元会，方业明，等.老年高血压患者心率变异性与血压晨峰现象［J］.中华高血压杂志，2008，16（11）:1039-1040.

［9］霍震，杜月君，罗怡.老年高血压患者血压晨峰现象分析［J］.中国老年学杂志，2008，28（7）:717.

［10］袁艳敏，郭艺芳.人体血压昼夜节律特征及其调节机制［J］.中华高血压杂志，2008，16（6）:483-485.

［11］Pinenta E，Gaddam KK，Pratt-Ubunama MN，et al. Aldosterone excess and resistance to 24-h blood pressure control［J］. J Hypertens，2007，25（10）:2131-2137.

［12］Neutel JM，Schumacher H，Gosse P，et al. Magnitude of the early morning blood pressure surge in untreated hypertensive patients: a pooled analysis［J］. J Clin Pract，2008，62（11）:1654-1663.

［13］张录兴，郑强荪，许新录，等.冠心病患者心率变异性昼夜变化观察［J］.心脏杂志，2003，15（2）:185.