Abstract:Atrial fibrillation(AF) is the most common public health problem. It has been revealed by research that inflammation and oxidative stress of cardiac muscle cell involve in the structural and electrical remodeling of atrium, which becomes the underlying pathogenesis of AF furtherly. Statins is a kind of 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor. Besides the efficacy of lipidlowering, statin drugs are also anti-inflammatory and antioxidativestress, which improves the remodeling of atrium and thus reduces the incidence of AF. However, the anti-arrhythmic property of statin has not been completely illuminated in clinical practice. Conclusions about its application in the primary or secondary prevention of AF remain controversial.
汪永生, 张晓红. 他汀应用于心房颤动防治的研究进展[J]. 实用心电学杂志, 2016, 25(3): 217-221.
WANG Yong-Sheng, ZHANG Xiao-Hong. Advances of research on statin’s application in atrial fibrillation control. JOURNAL OF PRACTICAL ELECTROCARDIOLOGY, 2016, 25(3): 217-221.
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