Abstract:Objective To observe the effects of pulmonary vein isolation(PVI) associated with complex fractionated atrial electrograms(CFAE) ablation on patients with persistent atrial fibrillation(AF).Methods Twenty-three patients with persistent AF were enrolled in the study. All of them had been treated by PVI and linear ablation in left atrium, among whom 12 cases were additionally given CFAE ablation. During a one-year follow-up, several indexes were compared between the two groups, including the duration of operation, X-ray exposure time, ablation time, surgical complications, internal diameter and thrombus of left atrium, success rate of once operation, etc.Results Compared with PVI group, the total time of operation [(176±22) min vs. (252±35) min], X-ray exposure time[(34±7.6) min vs. (42±9.1) min], and ablation time[(63±8) min vs. (94±11) min] was significantly increased in PVI+CFAE group(P<0.05). The differences of surgical complications, and the influences on internal diameter and thrombus of left atrium were not statistically significant. The success rate of once operation in PVI associated with CFAE ablation group was significantly higher than that in PVI group (75% vs. 64%; P<0.05). Conclusion In the treatment of persistent atrial fibrillation, although PVI associated with CFAE ablation lengthens the time of operation, X-ray exposure time, and ablation time, it will not increase the incidence of complications and can elevate the success rate of once operation in atrial fibrillation ablation.
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