Abstract：Objective To analyze the ECG changes of HIV/AIDS patients before and after antiviral therapy, and to explore the impact of antiviral drugs on hearts electrical activity.Methods The enrolled 130 HIV/AIDS patients were divided into three groups according to the duration of antiviral therapy: group A(1-3 years of antiviral therapy), group B(4-6 years of antiviral therapy), and group C(7-10 years of antiviral therapy). Routine electrocardiograms(ECGs) before and after the treatment were comparatively analyzed.ResultsBefore and after antiviral therapy, the differences of incidence rates of normal ECG, sinus tachycardia, and abnormal ECG in group C were statistically significant(P<0.05). In group A and group B, after antiviral therapy, the incidence rates of abnormal ECG, STT changes, sinus bradycardia, left axis deviation, and left ventricular high voltage all increased than before, however, without statistically significant differences(P>0.05).Conclusion HIV and highintensive antiviral therapy obviously damage heart's electrical activity, which is closely related to progression of the disease and the duration of antiviral therapy.
2014, Vol. 23 
