Abstract:Objective To investigate the effect of amiodarone and perindopril on cardioversion in elderly patients with persistent atrial fibrillation. Methods A total of 92 elderly patients with persistent atrial fibrillation were randomly divided into two groups, conventional treatment group and combined treatment group, with 46 cases in each group. For restoration of sinus rhythm, conventional treatment group took amiodarone while combined treatment group received perindopril (4 mg/d) additionally. The rate and the average time of cardioversion within 4 weeks between the two groups was observed and compared. Results The rate of cardioversion within 4 weeks in combined treatment group was significantly higher than that of conventional treatment group, with significantly shorter average cardioversion time, and both the differences were statistically significant(P<0.05).Conclusion Amiodarone combined with perindopril can significantly improve cardioversion rates for elderly patients with persistent atrial fibrillation and shorten the average time of cardioversion.
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