Abstract: Objective To investigate the efficacy of circumferential pulmonary vein isolation guided by Ensite3000 3D mapping system in patients with atrial arrythmia. Methods Consecutive patients with atrial arrhythmia underwent circumferential pulmonary vein isolation guided by Ensite3000 3D mapping system. Disappearance of pulmonary vein potential was considered as the ablation endpoint.Success was defined as without atrial tachyarrhythmia after 3 months,as well as asymptomatic atrial tachyarrhythmia. Results Clinical success achieved 71.8% and the effective rate was 12.6% in 64 patients. Severe complications included 2 cases of pericardial tamponade and 2 cases of mild pericardial effusion,1 case of femoral embolism and 1 case of arteriovenous fistula. There was no death case. Conclusion Circumferential pulmonary vein isolation guided by Ensite3000 3D mapping system is an effective therapy and safe for patients with atrial arrhythmia.
[1] Haissaguerre M,Jais P,Shah DC,et al. Spontaneous initiation of atrial fibrillation by ectopic beats originating in the pulmonary veins[J]. N Engl J Med, 1998,339(10):659-666. [2] Fuster V,Ryden LE,Cannom DS,et al. ACC/ AHA/ ESC 2006 guidlines for the management of patients with atrial fibrillation-executive summary : a report of the American college of cardiology / American Heart Association Task Force on Practice Guidelines and the European Society of Cardiology Committee for Practice Guidelines(Writing Committee to Revise the 2001 Guidelines for the Management of Patients With Atrial Fibrillation)[J]. J Am Coll Cardiol,2006,48(4):854-906. [3] Pappone C,Santinelli V,Manguso F,et al. Pulmonary vein denervation enhances long term benefit after circumferential ablation for paroxysmal atrial fibrillation[J]. Circulation,2004,109(3): 327-334. [4] Ouyang F,Antz M,Ernst S,et al. Recovered pulmonary vein conduction as a dominant factor for recurrent atrial tachyarrhythmias after complete circular isolation of the pulmonary veins: lessons from double Lasso technique[J]. Circulation,2005,111(2):127-135.