Modeling and simulation of systemic circulation system
1.Institute of Biomedical Engineering, Jiangsu University, Zhenjiang, Jiangsu 212013, China; 2.School of Electrical and Information Engineering, Jiangsu University, Zhenjiang， Jiangsu 212013, China
Abstract：According to the equivalent relations of fluid network, electrical network, current, resistors, capacitors and inductors were respectively represented by blood flow, hydraulic viscous resistance, compliance and inertance. The left ventricle was modeled by a timevarying capacitance and myocardial impedance to establish fifthorder lumped parameter systemic circulation electric circuit model. Based on the real physiological conditions and clinical data of human being, the model parameters were determined. The hemodynamics of normal heart and failure heart caused by different part diseases were simulated to investigate the bionic control mechanism of heart failure, and to verify the feasibility of the proposed model. According to basic circuit analysis methods, the state equations were deduced and simulated by MATLAB. The results show that the modified left ventricle can comprehensively reflect the working mechanism and function of heart, and can simulate the hemodynamics of normal heart. The hemodynamics of the heart failure caused by left ventricle elastance, systemic vascular resistance or myocardial impedance can be simulated by changing model parameters.
引用本文:
钱坤喜1, 刘苓苓1, 李岚2, 王芳群2. 体循环系统建模与仿真[J]. 江苏大学学报（自然科学版）, 2012, 33(3): 278-282.
Qian Kunxi1, Liu Lingling1, Li Lan2, Wang Fangqun2. Modeling and simulation of systemic circulation system[J]. Journal of Jiangsu University(Natural Science Eidtion)
, 2012, 33(3): 278-282.
2012, Vol. 33 
