Recognition property and mechanism of molecularly imprinted polymers of Apigenin
1.School of Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang, Jiangsu 212013, China; 2.School of Material Science and Engineering, Jiangsu University, Zhenjiang, Jiangsu 212013, China)
Abstract：The molecularly imprinted polymers with Apigenin as template molecule were prepared by molecular imprinting technique using 2-vinylpyridine as a functional monomer and EDMA as a crosslinker. The noncovalent interaction between Apigenin and 2-vinylpyridine were determined by UV spectrometry. Apigenin imprinted polymer′s binding affinity and selectivity to Apigenin were evaluated by equilibrium adsorption experiments and its adsorption kinetics were observed. The results show that Apigenin imprinted polymer could specially recognize Apigenin molecule through electrostatic interaction and exhibited higher affinity to Apigenin. Scatchard analysis indicated that there were two classes of recognition sites in Apigenin imprinted polymer, which had different affinity to Apigenin. Furthermore, compared to the adsorption behaviors of Apigenin and its analogs, Apigenin imprinted polymer displayed satisfying selectivity. The selective adsorption of Apigenin on MIP could be accomplished in 15 h.
2010, Vol. 31 
