Abstract: Due to the constant growing of subway traffic volume, the interchange stations as hubs of subway system are suffering from severe congestion, especially for the interchange stations in "crossover" form. The buffer areas were proposed to alleviate the problem of station congestion. Based on Anylogic software, the massive data simulations were conducted to discover the law of congestion formation in "crossover" passages. The regional buffer model was established to obtain the flow-buffer area formulas by orthogonal analysis. The system arrival model was set up, and based on the evaluation indicators of passenger flow density and theoretical arrivals, the empirical research was applied on Nanjing Daxing Gong station to check the proposed method. The results show that setting up a small buffer area can greatly alleviate the congestion of "crossover" transfer channel, and even minimal buffer area can improve the traffic capacity of Nanjing Daxing Gong station by 30%.