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Effects of a cinnamon extract on plasma glucose in diabetes mellitus type 2 |
| LU Ting1，2, SHENG Hong-guang 2 |
(1.School of Clinical Medicine, Jiangsu University, Zhenjiang Jiangsu 212001; 2.Department of Endocrinology, Xuhui District Central Hospital, Shanghai 200031, China) |
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Abstract Objective: To investigate cinnamon extract as a supplemental medication for the treatment of type 2 diabetes. Method: A total of 43 patients with type 2 diabetes were divided into cinnamon group(n=23) and control group(n=20)at random.On the basis of original drug treatment, the cinnamon group does additional medication of cinnamon tablet with a dose of 120 mg／d and the control group took placebo.Before and after treatment, both groups had their fasting plasma glucose, glycosylated hemoglobin(glycated haemoglobin Alc, HbA1c), serum creatinine, transaminases and blood lipid levels measured. Result: The fasting plasma glucose, glycated haemoglobin Alc(HbA1c)and triglyceride in the cinnamon groups were reduced significantly after treatment whereas the placebo group showed no remarkable change.The low-density lipoprotein(LDL-C), high-density lipoprotein(HDL-C),serum creatinine and aspartate aminotransferase(AST) in the cinnamon group showed no remarkable change after the experiment. The alanine aminotransferase(ALT) and total cholesterol of the placebo group significantly raised after treatment(P<0.05).Conclusion: Additional medication of cinnamon was effective in reducing the fasting plasma glucose, triglyceride and glycated haemoglobin Alc in patients with type 2 diabetes,and the toxic side effects were very low.
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Received: 12 September 2012
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2013, Vol. 23 
