PCV-VG联合PEEP对胸腔镜下行肺癌根治术患者的肺保护作用

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Abstract [Abstract]Objective: To evaluate the effects of pressure controlled ventilationvolume guaranteed (PCVVG) combined with positive endexpiratory pressure (PEEP) on hemodynamics, respiratory mechanics, and oxygenation in patients with pulmonary carcinoma undergoing thoracoscopic radical resection. Methods: Forty patients with lung cancer undwent thoracoscopic lung radical resection were randomly divided into 2 groups: in routine group, both two lung ventilation and one lung ventilation were performed, patients received the ventilation protocol consisting of 8 mL/kg VT, 0 cmH2O PEEP under volume controlled ventilation (VCV), while in combination group, patients received 8 mL/kg VT, PEEP 5 cmH2O under PCVVG. Invasive arterial systolic blood pressure(ASBP) and diastolic blood pressure(ADBP) and heart rate were monitored and recorded at baseline(T0), at the time just before one lung ventilation (T1), at 30 min (T2), 60 min (T3), 120 min after one lung ventilation (T4) and 30 min after the restoration of two lung ventilation (T5). PPeak, PPlat, Cdyn were monitored and recorded at the selected time points, arterial blood samples were collected at T1-T5 time points for blood gases analyse and oxygenation index was calculated. Results: The patterns of hemodynamic parameters were similar between the two groups(P>0.05). Compared with routine group, PPeak, PPlat in combination group were significantly decreased at T2-T5 (P<0.05), while Cdyn, PaO2 and oxygenation index at T1-T5 were significantly higher(P<0.05). Conclusion: PCVVG combined with PEEP could provide stable hemodynamics, improve respiratory mechanics and further increase oxygenation for patients with lung carcinoma undergoing thoracoscopic radical resection.

Received: 17 July 2019

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	GAO Rong
	BIAN Qing-ming

Cite this article:

GAO Rong,BIAN Qing-ming.

Protective effects of PCV-VG combined with PEEP on lungs in patients with lung carcinoma undergoing thoracoscopic radical resection

[J]. Journal of Jiangsu University(Medicine Edition), 2020, 30(01): 68-71.

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http://zzs.ujs.edu.cn/xbyxb/EN/ OR http://zzs.ujs.edu.cn/xbyxb/EN/Y2020/V30/I01/68

［1］FernandezPerez ER, Keegan MT, Brown DR, et al. Intraoperative tidal volume as a risk factor for respiratory failure after pneumonectomy\[J\]. Anesthesiology, 2006, 105(1): 14-18.

［2］Lohser J, Slinger P. Lung injury after onelung ventilation: A review of the pathophysiologic mechanisms affecting the ventilated and the collapsed lung\[J\]. Anesth Analg, 2015, 121(2): 302-318.

［3］Kim KN, Kim DW, Jeong MA, et al. Comparison of pressurecontrolled ventilation with volumecontrolled ventilation during onelung ventilation: a systematic review and metaanalysis\[J\]. BMC Anesthesiol, 2016, 16(1):72.

［4］Tan J, Song ZH, Bian QM, et al. Effects of volumecontrolled ventilation vs. pressurecontrolled ventilation on respiratory function and inflammatory factors in patients undergoing videoassisted thoracoscopic radical resection of pulmonary carcinoma\[J\]. J Thorac Dis, 2018, 10(3):1483-1489.

［5］Lin F, Pan LH, Qian W, et al. Comparison of three ventilatory modes during onelung ventilation in elderly patients \[J\]. Int J Clin Exp Med, 2015, 8(6): 9955-9960.

［6］Pu J，Liu Z，Yang L，et al．Applications of pressure control ventilation volume guaranteed during onelung ventilation in thoracic surgery \[J\]. Int J Clin Exp Med, 2014, 7(4): 1094-1098.

［7］Song SY, Jung JY, Cho MS, et al. Volumecontrolled versus pressurecontrolled ventilationvolume guaranteed mode during onelung ventilation\[J\]. Korean Anethesiol, 2014, 67(4):258-263.

［8］Blank RS, Colquhoun DA, Durieux ME, et al. Management of onelung ventilation: impact of tidal volume on complications after thoracic surgery\[J\]. Anesthesiology, 2016, 124(6):1286-1295.

［9］Kim N, Lee SH, Choi KW, et al. Effects of positive endexpiratory pressure on pulmonary oxygenation and biventricular function during onelung ventilation: a randomized crossover study \[J\]. J Clin Med, 2019, 8(5). pii: E740.