Authenticity identification of famous and precious animal medicine tortoiseshell by terahertz time-domain spectroscopy#br#
JIANG Jun1,2, ZENG Yichen2, CHEN Zhiying2, PEI Dan3, HE Jinjin2, TANG Haifa4, CAO Yunfei3, CAI Hui1
（1. Department of Integrated Chinese and Western Medicine, General Hospital of Eastern Theater Command of PLA, Nanjing Jiangsu 210002; 2. School of Pharmacy, Jiangsu University, Zhenjiang Jiangsu 212013; 3. Zhenjiang Food and Drug Supervision and Inspection Center, Zhenjiang Jiangsu 212000; 4. Yangzijiang Pharmaceutical Group Co. LTD, Taizhou Jiangsu 225321, China）
Abstract：Objective： To establish a new method for identification of true and false tortoiseshells by terahertz timedomain spectroscopy and stoichiometry. Methods： The samples of authentic tortoiseshell and fake tortoiseshell from the redeared slider were selected for further experiments. The typical characteristics of the two samples were compared by classical character identification and microscope identification methods, and then the spectral information of the samples was measured by terahertz timedomain spectrometer. The sample spectra were smoothprocessed and baseline calibrated, and the data were analyzed by stoichiometric method to distinguish the authentic tortoiseshells from the fake tortoiseshells. Results： The results of character identification showed that there were only slight differences between intact and fake tortoiseshell samples, and little differences in fragments or powder. Microscopic identification of the two samples did not find obvious characteristic difference structure. After fast Fourier transform filter and orthogonal partial least square discriminant analysis, the terahertz timedomain spectral curves of the two samples showed significant differences. Conclusion： Terahertz timedomain spectroscopy combined with orthogonal partial least square discriminant analysis could achieve accurate identification of true and false tortoiseshells.
