Association of atrial fibrillation with long R-R intervals with obstructive sleep apnea syndrome
XUE She-liang1, ZHOU Yan-juan2 , ZHUANG Zhi-fang2, CAI Gao-jun1, SHI Gan-wei1 ,WENG Wei-jing1
(1. Department of Cardiology; 2. Department of Pulmonary Disease, the Affiliated Wujin Hospital of Jiangsu University, Changzhou Jiangsu 213002, China)
Abstract:Objective: To study the association of atrial fibrillation (AF) with long RR intervals with obstructive sleep apnea syndrome(OSAS). Methods: A total of 126 AF patients were enrolled and evaluated for Holter and polysomnography examination. All patients were divided into two groups according to whether long RR intervals (more than 2.5 seconds) occurred or not. Results: One hundred and six AF patients were divided into case group(38 cases) and control group (88 cases). There were no statistical significance difference between the age, gender, body mass index(BMI), smoking history, and complications of the 2 groups(P>0.05). The incidence of OSAS in case group was 71.1% (27/38), which was higher than that of the control group [45.5%(40/88),P<0.05]. Apnea hypopnea index(AHI) was (16.1±12.1) times/h and longest apnea time (20.0±12.3) seconds respectively in case group, which was higher than in control group (P<0.05). Pearson correlation analysis showed that OSAS and AHI were associated with incidences of long RR intervals in atrial fibrillation(P<0.05). Multivariable logistic regression analysis showed that AHI was an independent risk factor for long intervals in atrial fibrillation . Conclusion: There is a high incidence of OSAS in atrial fibrillation patients combination with long RR intervals. A higher AHI value could predict an increase in the incidence of long intervals in atrial fibrillation.
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