Abstract:Objective: To evaluate the safety and superiority of laparoscopy-assisted radical gastrectomy (LARG) for gastric cancer after endoscopic submucosal dissection (ESD). Methods: A total of 61 patients who underwent laparoscopicassisted radical gastrectomy (LARG group, n=41) or open radical gastrectomy(open group, n=20) for gastric cancer after ESD were retrospectively analyzed. The general data, indicators related to the operation and postoperative recovery of relevant information of two group patients were analyzed. Results: There were no differences in the age, gender, length of the tumor to the cut edge, number of cleaning lymph nodes, pathological staging, intraoperative injury, postoperative complications between LARG group and open group (both P>0.05). Compared with the open group, LARG group had longer operative time and higher expenditure (both P<0.01), but lower C-reactive protein, shorter scar,less blood loss,less postoperative pain-killers, shorter time for first flatus, and for unplugging gastrointestinal decompression, shorter time to tolerance of soft diet, and for unplugging the peritoneal drainage tube and faster postoperative recovery(both P<0.05). Conclusion: Laparoscopic-assisted radical gastrectomy is a feasible, safe, efficient and minimal invasive procedure for gastric cancer therapy after ESD.
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