Abstract:Immune checkpoint inhibitors (ICIs) occupy a core position in tumor immunotherapy, and greatly improve the prognosis of tumor patients. However, with the deepening of clinical practice, it has been found that ICIs can not only activate the immune system, but also cause many adverse reactions, especially leading to a variety of cardiovascular toxicity and increased cardiovascular mortality. This paper reviews the clinical manifestations, pathogenesis, diagnosis and treatment, etc. of ICIsinduced cardiovascular toxicity, which provides evidences for preventing cardiovascular injury and improving cardiac function.
詹洪吉,刘红霞,谭梦琴,王福军. 要高度重视免疫检查点抑制剂相关心血管不良反应的诊治[J]. 实用心电学杂志, 2024, 33(6): 541-547.
ZHAN Hongji, LIU Hongxia, TAN Mengqin,WANG Fujun. Pay attention to diagnosis and treatment of cardiovascular adverse reactions associated with immune checkpoint inhibitors. JOURNAL OF PRACTICAL ELECTROCARDIOLOGY, 2024, 33(6): 541-547.