Abstract：ObjectiveTo analyze the ECG changes and their clinical significance in patients with breast cancer after radiotherapy. MethodsRetrospective analysis was performed on 103 patients with breast cancer. The ECG indexes of heart rate, PR interval, QRS duration, QT interval, QTc, Sokolow-Lyon index(SLI), ST segment and T wave before radiotherapy (group A), within 3 months after radiotherapy (group B) and more than 3 months after radiotherapy (group C) were analyzed. ResultsAfter radiotherapy, PR interval is gradually extended and there is statistically significant difference between group A and group C (P<0.01); QRS duration is gradually prolonged, and QRS duration of group C varies significantly from either group A or group B (P<0.01); QTc is gradually reduced, however, QTc of group C does not vary significantly from either group A or group B. SLI in group B is lower than that in group A with statistically significant difference (P<0.01). After radiotherapy, the patients with significantly low, flat and inverted T wave compared with that before radiotherapy account for as high as 330%.The difference of the number of patients with T wave abnormalities before and after radiotherapy is statistically significant (P<0.05). ConclusionChanges of ECG indexes before and after radiotherapy may indicate changes of myocardial conduction and depolarization; abnormal T wave may indicate problems such as abnormal myocardial blood supply in an early stage. These changes are mostly not accompanied with clinical manifestations, but may indicate radiotherapy induced myocardial damage among breast cancer patients in an early stage. Regular ECG monitoring might aid in detecting early cardiotoxicity during followup after radiotherapy.
付争艳，尹希，耿旭红，潘烁，周凯，赵鹏. 乳腺癌放疗患者临床心电图分析[J]. 实用心电学杂志, 2022, 31(4): 253-255.
FU Zhengyan, YIN Xi, GENG Xuhong, PAN Shuo, ZHOU Kai, ZHAO Peng. Clinical ECG analysis of patients with breast cancer after radiotherapy. JOURNAL OF PRACTICAL ELECTROCARDIOLOGY, 2022, 31(4): 253-255.
