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| Levels and the clinical significance of sFlt-1 levels in the early acute coronary syndrome patients |
| GONG Jie, ZHANG Yu, LI Jian, YANG Zhen-yu |
| （Department of Cardiology, Wuxi People′s Hospital Affiliated to Nanjing Medical University, Wuxi Jiangsu 214023, China)
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Abstract Objective: To explore the clinical values of the peripheral soluble fmslike tyrosine kinase receptor 1(sFlt1) levels in early acute coronary syndrome(ACS) patients. Methods: A total of 150 patients who were admitted to hospital in six hours after chest pain occurred were recruited and divided into control group (n=48) or acute coronary syndrome group(ACS, n=102), plasma sFlt1 were detected and compared between the two groups. Receiver operating characteristic(ROC) curve and area under curve(AUC) were analysed with SPSS 20.0 statistical software. Results: The levels of plasma sFlt1 in ACS group were significantly higher compared with that of the control group\[(361.7±288.0) pg/mL vs (126.2±49.6)pg/mL,P<0.01\]. For the diagnosis of ACS, the AUC of sFlt1 was 0.852. Conclusion: Plasma sFlt1 was significantly elevated in the early ACS patients, and it could be one of the earliest sensitive indicators in the diagnosis and risk estimation of ACS.
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Received: 04 November 2016
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GUO Jun-fang, ZHANG Bao-wei, CHEN Rong, WANG Ying-ying, WANG Cheng-hua, TAO Ai-bin, BAO Zhong-hua, ZHANG Guo-hui, YIN Chun-yang. Clinical significance of plasma D-dimer level in differentiating acute aortic dissection from non STsegment elevated acute coronary syndrome[J]. Journal of Jiangsu University(Medicine Edition), 2018, 28(04): 316-319. |
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2017, Vol. 27 
