Abstract：Objective: To explore the relationship between microalbuminuria, serum thyroid stimulating hormone (TSH) level and type 2 diabetic patients(T2DM) with nonalcoholic fatty liver disease(NAFLD). Methods: A total of 254 T2DM patients were divided into the T2DM group (type 2 diabetic patients without NAFLD, n=124) and the NAFLD group (T2DM patients with NAFLD, n=130). All the subjects' general clinical data and hematological parameters were collected, SPSS 16.0 software were used for statistical analysis. Results: Age, disease course, height, SBP, DBP，LDL-c, HDL-c, RBC, WBC, PLT and HbA1c had no statistical significance between two groups(P>0.05). The body weight, body mass index(BMI), WHR，triglyceride, total cholesterol, ALT, AST, microalbuminuria, TSH, and HOMA-IR had a statistically significant difference between two groups(P<0.05).With NAFLD as the dependent variable, univariate Logistic regression results showed that the body weight, BMI, WHR, total cholesterol, triglyceride, microalbuminuria, TSH were associated with NAFLD; Multivariate Logistic regression results showed that TSH, BMI, WHR, microalbuminuria were the independent influencing factor for NAFLD. Conclusion: In patients with T2DM, microalbuminuria, TSH, BMI, WHR were the independent influencing factors for NAFLD.
［Key words］type 2 diabetes mellitus; nonalcoholic fatty liver disease; microalbuminuria; thyroid stimulating hormone
2017, Vol. 27 
