［1］刘小琴,陈春华,申红玉,等.辅助性T淋巴细胞17及相关因子在慢性乙型肝炎病毒感染中的作用\[J\].中华传染病杂志, 2013,31(9): 552-554.［2］Liu Y,Verma VK,Malhi H,et al. Lipopolysaccharide downregulates macrophagederived IL22 to modulate alcoholinduced hepatocyte cell death\[J\]. Am J Physiol Cell Physiol,2017,313(3):C305-C313.［3］Jie Z,Liang Y,Yi P,et al.Retinoic acid regulates immune responses by promoting IL22 and modulating S100 proteins in viral hepatitis\[J\]. J Immunol, 2017,198(9):3448-3460.［4］Mo R,Wang P, Lai R, et al. Persistently elevated circulating Th22 reversely correlates with prognosis in HBVrelated acuteonchronic liver failure\[J\]. J Gastroenterol Hepatol, 2017,32(3):677-686.［5］莫瑞东,项晓刚,王芃,等.辅助性T淋巴细胞及其效应分子在慢性乙型肝炎患者疾病加重过程中的变化和作用\[J\].中华传染病杂志, 2014,32(4): 209-213.［6］孙伟,邹美银,秦刚,等.外周血Th22和Th17细胞对HBV相关性肝衰竭的预测价值\[J\].中华实用诊断与治疗杂志, 2015, 9(1):59-61.［7］中华医学会肝病学分会,中华医学会感染学分会.慢性乙型肝炎防治指南\[J\].临床肝胆病杂志,2015, 31(12):1941-1960.［8］中华医学会感染病学分会肝衰竭与人工肝学组,中华医学会肝病学分会重型肝病与人工肝学组.肝衰竭诊治指南（2012版）\[J/CD\].中华肝脏病杂志, 2013,21(4):193-202.［9］Jia L,Wu C. The biology and functions of Th22 cells\[J\]. Adv Exp Med Biol, 2014,841:209-230.［10］Yang XY, Wang HY, Zhao XY, et al.Th22, but not Th17 might be a good index to predict the tissue involvement of systemic lupus erythematosus\[J\]. J Clin Immunol, 2013,33(4):767-774.［11］Qin S, Ma S, Huang X,et al.Th22 cells are associated with hepatocellular carcinoma development and progression\[J\]. Chin J Cancer Res,2014,26(2):135-141.［12］Gao W,Fan YC,Zhang JY,et al. Emerging role of interleukin 22 in hepatitis B virus infection: a doubleedged sword\[J\]. J Clin Transl Hepatol,2013,1(2):103-108.［13］Radaeva S, Sun R, Pan HN, et al. Interleukin 22(IL22) plays a protective role in T cellmediated murine hepatitis: IL22 is a survival factor for hepatocytes via STAT3 activation\[J\]. Hepatology,2004,39 (5): 1332-1342.［14］Feng D, Kong X, Weng H, et al. Interleukin22 promotes proliferation of liver stem/progenitor cells in mice and patients with chronic hepatitis B virus infection\[J\].Gastroenterology,2012,143(1):188-198.［15］Xing WW, Zou MJ, Liu S, et al. Hepatoprotective effects of IL22 on fulminant hepatic failure induced by dgalactosamine and lipopolysaccharide in mice\[J\].Cytokine,2011,56(2):174-179.［16］Zhang Y, Cobleigh MA, Lian JQ,et al.A proinflammatory role for interleukin22 in the immune response to hepatitis B virus\[J\]. Gastroenterology,2011,141(5):1897-1906.
2019, Vol. 29 
