(1.Department of Respiratory, 2.Department of Thoracocardiac Surgery, 3.Department of Pathology, the Affiliated Wujin Hospital of Jiangsu University, Changzhou Jiangsu 213002, China)
Abstract：Objective: To evaluate the clinical value and safety of transbronchial needle aspiration(TBNA) in mediastinal restaging of non-small cell lung cancer(NSCLC) after neoadjuvant chemotherapy. Methods: In 15 NSCLC patients with suspected N2 lymph node metastasis by chest CT scan, TBNA was performed for two times, before and after chemotherapy. The cytological results were compared with post-operative pathology. Results: Overall diagnostic sensitivity, specificity, accuracy, positive predictive value and negative predictive value of TBNA in mediastinal restaging after neoadjuvant chemotherapy were 80.6％, 100％, 87.2％, 100％ and 72.7％. The overall coincidence rate of pathologic typing was 80％. The overall accuracy of c-N by TBNA was 86.7 ％(13／15). Serious complications were not observed in all patients. Conclusion: TBNA is an accurate and safe method for mediastinal restaging of NSCLC, which has certain clinical application value.
收稿日期: 2012-11-22
基金资助:
江苏大学临床医学科技发展基金资助项目(JLY20100027)
通讯作者:
周燕娟：swallowjuan@mail.com,主要从事慢性阻塞性肺疾病研究。
作者简介: 周尧（1978—），男，江苏常州人，医师，医学学士，主要从事支气管镜介入方面等研究
引用本文:
周尧1, 庄志方1, 姜敏炎2, 薛志新3, 仇铁峰1, 朱小波2, 凌夏君1, 缪小辉1, 蒋一雅1, 钟亚花1, 印秀丽1, 周燕娟1. 经支气管针吸活检在ⅢA-N2期非小细胞肺癌新辅助化疗纵隔再分期中的应用[J]. 江苏大学学报:医学版, 2013, 23(1): 69-71,74.
ZHOU Yao1, ZHUANG Zhi-fang1, JIANG Min-yan2, XUE Zhi-xin3, QIU Tie-feng1, ZHU Xiao-bo2, LING Xia-jun1, MIAO Xiao-hui1, JIANG Yi-ya1, ZHONG Ya-hua1, YIN Xiu-li1, ZHOU Yan-juan1. Role of transbronchial needle aspiration in mediastinal restaging of ⅢA-N2 non-small cell lung cancer after neoadjuvant chemotherapy. Journal of Jiangsu University(Medicine Edition), 2013, 23(1): 69-71,74.
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