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Advances in research of QT interval prolongation and poor prognosis among patients with corona virus disease 2019 |
WANG Yue, CHEN Shuning, WANG Deguo |
(Department of Gerontology, the First Affiliated Hospital of Wannan Medical College, Wuhu Anhui 241001, China) |
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Abstract In recent years, with the worldwide pandemic of corona virus disease 2019 (COVID-19), the safety of anti-infection drugs arouses more and more attention. Hydroxychloroquine alone or combined with azithromycin could cause prolonged QT interval in the ECGs of patients with COVID-19, which may induce severe arrhythmia. According to the clinical evidences reported at home and abroad, the changes of QT interval in COVID-19 patients should be strictly monitored. This paper reviews on the drugs leading to prolonged QT interval, inflammation, age and other factors in COVID-19 patients, and their impact on the prognosis, in order to provide references for clinicians to optimize the treatment options of COVID-19 patients.
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