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| Risk stratification of patients with primary arrhythmia
syndrome |
| Arthur AM Wilde |
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Abstract Primary arrhythmia syndromes mainly include long QT syndrome（LQTS), Brugada syndrome, catecholaminergic polymorphic ventricular tachycardia(CPVT). Because of high risk of sudden death, it is extremely important to diagnose and stratify primary arrhythmia syndromes as early as possible. It is relatively easy to determine individuals at extremely high risk or low risk, but it is difficult to stratify most of the patients at moderate risk. Genetic analysis and clinical evaluation of the disease are necessary for risk stratification. Combined with clinical cases, this article focuses on the risk stratification of LQTS, Brugada syndrome and CPVT. The risk factors for stratification of LQTS include QTc, marked changes of T wave and gene mutation. The risk factors for stratification of Brugada syndrome include gene mutation and fragmented QRS complex. Risk stratification factors for CPVT include medical history of cardiac arrest, age of onset and whether beta blockers are used. In addition, the relationship between lamin A/C cardiomyopathy and primary arrhythmia syndromes is also discussed.
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2018, Vol. 27 
